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1. 歯性感染症の疫学、病因、および臨床症状 epidemiology pathogenesis and clinical manifestations of odontogenic infections
2. 感染性心内膜炎の疫学、危険因子および微生物学 epidemiology risk factors and microbiology of infective endocarditis
3. 頚部顔面の放線菌症 cervicofacial actinomycosis
4. 歯性感染症の合併症、診断、および治療 complications diagnosis and treatment of odontogenic infections
5. 培養陰性感染性心内膜炎の疫学、微生物学、および診断 epidemiology microbiology and diagnosis of culture negative endocarditis

The peri-implant health in patients attending an annual recall program. A clinical and microbiological study in 74 patients from the Tübingen Implant Registry.

Lachmann S, Stehberger A, Axmann D, Weber H.SourceDepartment of Oral and Maxillofacial Surgery, Center of Dentistry, Oral Medicine and Maxillofacial Surgery, University Hospital Tübingen, Tübingen, Germany; Department of Prosthodontics and Medical Material Sciences, Center of Dentistry, Oral Medicine and Maxillofacial Surgery, University Hospital Tübingen, Tübingen, Germany.
Clinical oral implants research.Clin Oral Implants Res.2013 Dec;24(12):1300-9. doi: 10.1111/j.1600-0501.2012.02573.x. Epub 2012 Aug 20.
OBJECTIVES: To describe the peri-implant condition of unselected implant recall patients, to relate it to relevant features from the patient medical history, and to look at associations across these findings.PATIENTS AND METHODS: Prior to their most recent recall appointment, 74 individuals underwen
PMID 22905716

Porphyromonas gingivalis, Treponema denticola and toll-like receptor 2 are associated with hypertensive disorders in placental tissue: a case-control study.

Chaparro A, Blanlot C, Ramírez V, Sanz A, Quintero A, Inostroza C, Bittner M, Navarro M, Illanes SE.SourceDepartment of Periodontology, Dentistry Faculty, Universidad de los Andes, Santiago, Chile.
Journal of periodontal research.J Periodontal Res.2013 Dec;48(6):802-9. doi: 10.1111/jre.12074. Epub 2013 May 28.
AIM(S): To explore the associations between the presence of periodontal pathogens and the expression of toll-like receptors (TLR-2 and TLR-4) in the placental tissue of patients with hypertensive disorders compared to the placentas of healthy normotensive patients.MATERIAL AND METHODS: A case-contro
PMID 23711357

Gene expression and phenotypic traits of Aggregatibacter actinomycetemcomitans in response to environmental changes.

Longo PL, Nunes AC, Umeda JE, Mayer MP.SourceDepartment of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Journal of periodontal research.J Periodontal Res.2013 Dec;48(6):766-72. doi: 10.1111/jre.12067. Epub 2013 Apr 18.
BACKGROUND AND OBJECTIVE: Periodontopathogens experience several challenges in the oral cavity that may influence their transcription profile and resulting phenotype. This study evaluated the effect of environmental changes on phenotype and gene expression in a serotype b Aggregatibacter actinomycet
PMID 23600969

Neutrophil-derived resistin release induced by Aggregatibacter actinomycetemcomitans.

Furugen Reiko,Hayashida Hideaki,Yoshii Yumiko,Saito Toshiyuki
FEMS Microbiology Letters 321(2), 175-182, 2011-08
… The present investigation demonstrated high levels of resistin in culture supernatants of neutrophils that are stimulated by a highly leukotoxic strain of Aggregatibacter actinomycetemcomitans. … actinomycetemcomitans-expressed leukotoxin induces extracellular release of human neutrophil-derived resistin by interacting with LFA-1 on the surface of neutrophils and, consequently, activating Src family tyrosine kinases. …
NAID 120003751834

成田好美,兒玉英也,篠原ひとみ,吉田倫子
母性衛生 52(2), 327-336, 2011-07
… 80名の妊婦の妊娠10〜13週と妊娠30〜35週に,唾液中のPorphyromons gingivalis(Pg菌),Tannerella forsythensis(Tf菌),Prevotella intermedia(Pi菌),Aggregatibacter actinomycetemcomitans(Aa菌)の存在をPCR-インベーダー法にてスクリーニングするとともに,口腔の歯周病関連症状(易出血,歯肉の腫れ,歯のぐらぐら感,口臭,口腔内の乾燥)について質問紙調査を行った。 …
NAID 110008687074