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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/04/08 19:46:48」(JST)

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  • Thiopurine metabolite testing in inflammatory bowel disease.
  • Goldberg R1,2, Moore G1,3, Cunningham G2, Schulberg J2, Marsh P1, Brown S2, Connell W2, Lust M2, Kamm MA2,4,5, Bell S2.
  • Journal of gastroenterology and hepatology.J Gastroenterol Hepatol.2016 Mar;31(3):553-60. doi: 10.1111/jgh.13210.
  • BACKGROUND: Thiopurine use in inflammatory bowel disease (IBD) is limited by drug toxicity and lack of therapeutic efficacy. We assessed the utility of thiopurine metabolite testing and the relationship between disease activity, dose, and metabolite levels in a real world setting.METHODS: Patients i
  • PMID 26510636
  • Allopurinol Use During Maintenance Therapy for Acute Lymphoblastic Leukemia Avoids Mercaptopurine-related Hepatotoxicity.
  • Giamanco NM1, Cunningham BS, Klein LS, Parekh DS, Warwick AB, Lieuw K.
  • Journal of pediatric hematology/oncology.J Pediatr Hematol Oncol.2016 Mar;38(2):147-51. doi: 10.1097/MPH.0000000000000499.
  • 6-Mercaptopurine (6-MP) is the mainstay of treatment for acute lymphoblastic leukemia and lymphoblastic lymphoma. It is metabolized into the pharmacologically active, 6-thioguanine nucleotide (6-TGN), and 6-methyl mercaptopurine nucleotides (6-MMPN), which is associated with hepatotoxicity that jeop
  • PMID 26808368
  • Pharmacokinetics of Chemotherapeutic Drugs in Pediatric Patients With Down Syndrome and Leukemia.
  • Hefti E1, Blanco JG.
  • Journal of pediatric hematology/oncology.J Pediatr Hematol Oncol.2016 Feb 22. [Epub ahead of print]
  • Children with Down syndrome (DS) have a 10- to 30-fold increased risk of developing acute myeloid leukemia or acute lymphoblastic leukemia. Patients with DS and leukemia are treated with the same chemotherapeutic agents as patients without DS. Treatment regimens for pediatric leukemia comprise multi
  • PMID 26907658


  • Efficient Thymidine-Selective DNA Interstrand Photo-activated Crosslinking by the 6-Thioguanine Connected <i>via</i> an Ethylene-Linker to the 2′-Deoxyribose Unit
  • CHEMICAL & PHARMACEUTICAL BULLETIN 64(9), 1315-1320, 2016
  • NAID 130005261564
  • The Achievement of Shuttle Vector Techniques in Mammalian Cell Mutation Research
  • Genes and environment : the official journal of the Japanese Environmental Mutagen Society 35(4), 93-98, 2013-11-20
  • NAID 10031196750
  • The Blood Concentration and Therapeutic Efficacy of Azathioprine in Patients Receiving Infliximab Combination Therapy for Refractory Crohn's Disease : A Clinical Study


[6-Thioguanine] [154-42-7] | 価格や在庫、物性値などの詳細情報ページです。 ... ・川口の在庫は即日,つくばの在庫は2〜3日以内の出荷となります。・詳細につきましては,お手数ですが営業部までお問い合わせください。
解説:小粒子LDLプロファイル(Small,Dense LDL Profile) ... 6-チオグアニンヌクレオチド(6-Thioguanine Nucleotide(s)) 6-チオグアニンヌクレオチド(6-TGN)は、6-メルカプトプリン(6-MP)やアザチオプリン(AZA)の代謝物である。


Thioguanine (Thioguanin™) is an  inquiry cart 6-Thioguanine CAS NO.154-42-7 converted to 6 mercaptopurine 6 mp by nonFigures in this Articletg 2 amino 6 mercaptopurine 2 amino 6 Thioguanine




6-thioguanine, 6-TG


  [★] チオグアニン

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「an antineoplastic drug used to treat acute leukemias」