6-hydroxydopamine

出典: meddic

6-ヒドロキシドパミン6-ハイドロキシドパミン

6-OHDAoxidopamine

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/07/02 11:52:37」(JST)

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英文文献

  • Protective and reversal effects of conserved dopamine neurotrophic factor on PC12 cells following 6-hydroxydopamine administration.
  • Mei J1, Niu C1.
  • Molecular medicine reports.Mol Med Rep.2015 Jul;12(1):297-302. doi: 10.3892/mmr.2015.3388. Epub 2015 Feb 24.
  • Conserved dopamine neurotrophic factor (CDNF), a member of the mammalian mesencephalic astrocyte-derived neurotrophic factor family of conserved secreted factors, has been reported to protect and rescue dopaminergic neurons in vivo. PC12 pheochromocytoma cells are widely used as a cell model for Pa
  • PMID 25738732
  • Evidence for a role for α6(∗) nAChRs in l-dopa-induced dyskinesias using parkinsonian α6(∗) nAChR gain-of-function mice.
  • Bordia T1, McGregor M1, McIntosh JM2, Drenan RM3, Quik M4.
  • Neuroscience.Neuroscience.2015 Jun 4;295:187-97. doi: 10.1016/j.neuroscience.2015.03.040. Epub 2015 Mar 24.
  • l-Dopa-induced dyskinesias (LIDs) are a serious side effect of dopamine replacement therapy for Parkinson's disease. The mechanisms that underlie LIDs are currently unclear. However, preclinical studies indicate that nicotinic acetylcholine receptors (nAChRs) play a role, suggesting that drugs targe
  • PMID 25813704
  • The role of catecholamine innervation in the medial prefrontal cortex on the regulation of body weight and food intake.
  • Gálosi R1, Hajnal A2, Petykó Z3, Hartmann G4, Karádi Z3, Lénárd L3.
  • Behavioural brain research.Behav Brain Res.2015 Jun 1;286:318-27. doi: 10.1016/j.bbr.2015.03.017. Epub 2015 Mar 14.
  • Effects of 6-hydroxydopamine (6-OHDA) lesions in the medial prefrontal cortex with or without protection of norepinephrine (NE) fibers were examined on basic regulatory processes of feeding. Daily body weight, food and water intake were measured. Locomotor activity, ingestion after food or water dep
  • PMID 25783808

和文文献

  • Nrf2-ARE経路活性化を介したドパミン神経保護作用の機序解析及びその活性化物質の探索
  • 泉 安彦
  • YAKUGAKU ZASSHI (藥學雜誌) 133(9), 983-988, 2013-09-00
  • … Treatment with lactacystin, a proteasome inhibitor, significantly suppressed 6-hydroxydopamine (6-OHDA)-induced toxicity and oxidative stress in PC12 cells. … In mesencephalic cultures, lactacystin-induced upregulation of HO-1 in astrocytes contributed to dopaminergic neuroprotection against 6-OHDA-induced toxicity. …
  • NAID 120005323877
  • Behavioral Performance at Early (4 Weeks) and Later (6 Months) Stages in Rats With Unilateral Medial Forebrain Bundle and Striatal 6-Hydroxydopamine Lesions
  • SUN Wei,SUGIYAMA Kenji,ASAKAWA Tetsuya,ITO-YAMASHITA Tae,NAMBA Hiroki
  • Neurologia medico-chirurgica 53(1), 7-11, 2013
  • … Our previous studies showed differences in striatal D2 receptor functional activity between two different rat parkinsonian models, with lesions induced by 6-hydroxydopamine injection in the striatum and in the medial forebrain bundle (MFB) at both early (4 weeks) and later (6 months) stages after lesioning. …
  • NAID 130003364188
  • Nrf2-ARE経路活性化を介したドパミン神経保護作用の機序解析及びその活性化物質の探索
  • 泉 安彦
  • YAKUGAKU ZASSHI 133(9), 983-988, 2013
  • … Treatment with lactacystin, a proteasome inhibitor, significantly suppressed 6-hydroxydopamine (6-OHDA)-induced toxicity and oxidative stress in PC12 cells. … In mesencephalic cultures, lactacystin-induced upregulation of HO-1 in astrocytes contributed to dopaminergic neuroprotection against 6-OHDA-induced toxicity. …
  • NAID 130003361984

関連リンク

6-ヒドロキシドーパミン(6-hydroxydopamine または 6-OHDA)は神経科学において ドーパミン作動性ニューロンおよびノルアドレナリン作動性ニューロンを選択的に変性 除去するために用いられる神経毒。6-OHDAは、ドーパミンおよびノルアドレナリンの再 ...

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★リンクテーブル★
リンク元6-ヒドロキシドパミン」「6-OHDA」「oxidopamine」「6-ハイドロキシドパミン
関連記事hydroxydopamine

6-ヒドロキシドパミン」

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6-hydroxydopamine6-OHDA
6-ハイドロキシドパミンオキシドパミン


6-OHDA」

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6-ヒドロキシドパミン

6-hydroxydopamineoxidopamine


oxidopamine」

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オキシドパミン

6-hydroxydopamine6-OHDA


6-ハイドロキシドパミン」

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6-hydroxydopamine
6-ヒドロキシドパミン


hydroxydopamine」

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ヒドロキシドパミン

OHDA




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