WordNet
- an enzyme that catalyses the biochemical reduction of some specified substance
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- 1. ステロイド5 -α-レダクターゼ2欠乏症 steroid 5 alpha reductase 2 deficiency
- 2. 糖尿病合併症の予防におけるアルドース還元酵素阻害剤 aldose reductase inhibitors in the prevention of diabetic complications
- 3. メトヘモグロビン血症の遺伝学および病因 genetics and pathogenesis of methemoglobinemia
- 4. ビタミンＫおよびγカルボキシグルタミン酸の合成 vitamin k and the synthesis of gamma carboxyglutamic acid
- 5. 前立腺肥大症の内科的治療 medical treatment of benign prostatic hyperplasia
English Journal
- Metabolic dysfunction in female mice with disruption of 5α-reductase 1.
- Livingstone DE1,2, Di Rollo EM3, Mak TC3, Sooy K3, Walker BR3, Andrew R3.
- The Journal of endocrinology.J Endocrinol.2017 Jan;232(1):29-36. Epub 2016 Sep 19.
- 5α-Reductases irreversibly catalyse A-ring reduction of pregnene steroids, including glucocorticoids and androgens. Genetic disruption of 5α-reductase 1 in male mice impairs glucocorticoid clearance and predisposes to glucose intolerance and hepatic steatosis upon metabolic challenge. However, it
- PMID 27647861
- Synthesis and biological evaluation of esters of 16-formyl-17-methoxy-dehydroepiandrosterone derivatives as inhibitors of 5α-reductase type 2.
- Sánchez-Márquez A1, Arellano Y1,2, Bratoeff E2, Heuze Y1, Córdova K2, Nieves G2, Soriano J3, Cabeza M1.
- Journal of enzyme inhibition and medicinal chemistry.J Enzyme Inhib Med Chem.2016 Dec;31(6):1170-6. doi: 10.3109/14756366.2015.1103235. Epub 2015 Nov 2.
- In this study, we investigated the in vitro effect of 16-formyl-17-methoxy dehydroepiandrosterone derivatives on the activity of 5α-reductase type 2 (5α-R2) obtained from human prostate. The activity of different concentrations of these derivatives was determined for the conversion of labelled tes
- PMID 26526826
- Novel dehydroepiandrosterone benzimidazolyl derivatives as 5α-reductase isozymes inhibitors.
- Arellano Y1, Bratoeff E2, Segura T2, Mendoza ME2, Sánchez-Márquez A1, Medina Y1, Heuze Y1, Soriano J3, Cabeza M1.
- Journal of enzyme inhibition and medicinal chemistry.J Enzyme Inhib Med Chem.2016 Dec;31(6):908-14. doi: 10.3109/14756366.2015.1070843. Epub 2015 Sep 23.
- 5α-R isozymes (types 1 and 2) play an important role in prostate gland development because they are responsible for intraprostatic dihydrotestosterone (DHT) levels when the physiological serum testosterone (T) concentration is low. In this study, we synthesized seven novel dehydroepiandrosterone de
- PMID 26394987
Japanese Journal
- 臨床的意義のあるN-結合型糖鎖生合成の初期過程における新たな発見
- 竹内 英之
- Trends in glycoscience and glycotechnology 22(126), 311-313, 2010-11-30
- NAID 10027893347
- 前立腺肥大症の薬物治療--5α還元酵素阻害薬の役割
- 酒井 英樹
- 臨床泌尿器科 64(10), 711-718, 2010-09
- NAID 40017259057
Related Links
- 5-alpha reductase deficiency is a condition that affects male sexual development before birth and during puberty. People with this condition are genetically male, with one X and one Y chromosome in each cell, and they have male ...
- Steroid 5-alpha-reductase 2 deficiency, a 46,XY disorder of sexual development (DSD), is an autosomal recessive condition in which 46,XY subjects with bilateral testes and normal testosterone formation have impaired virilization ...
Related Pictures
★リンクテーブル★
| リンク元 | 「5α還元酵素」 |
| 拡張検索 | 「testosterone 5alpha-reductase」「cholestenone 5alpha-reductase」「steroid 5alpha-reductase」 |
| 関連記事 | 「reductase」 |
「5α還元酵素」
- 英
- 5α reductase, 5α-reductase, 5-alpha reductase, 5-alpha-reductase, 5alpha-reductase
- 同
- 5α-リダクターゼ、5α-還元酵素
- 関
- リダクターゼ
臨床関連
「testosterone 5alpha-reductase」
- 関
- SRD5A2、testosterone 5-alpha-reductase
「cholestenone 5alpha-reductase」
「steroid 5alpha-reductase」
「reductase」
- n.