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1. プロトンポンプ阻害薬：胃酸分泌が関与する疾患への使用と副作用の概要proton pump inhibitors overview of use and adverse effects in the treatment of acid related disorders [show details]
… standard or high-dose PPI (eg, omeprazole 40 mg daily or twice daily), we decrease the dose by 50 percent every week. For patients on twice daily dosing,… review will provide an overview of the mechanism of action, pharmacokinetics, administration, and adverse effects of PPIs. The use and efficacy of PPIs in specific acid-related disorders is presented separately …
2. 炎症性腸疾患へのアザチオプリン、メルカプトプリンの投与の概要overview of azathioprine and mercaptopurine use in inflammatory bowel disease [show details]
… experience treatment-related leukopenia or other adverse effects (eg, abnormal liver chemistries) after initiating low dose thiopurine (AZA or 6-MP 50 mg daily). While AZA and 6-MP are well-tolerated in …
3. ピラジンアミド：概要pyrazinamide an overview [show details]
…therapy (DOT). Adult DOT regimens consist of either 50 mg/kg (maximum 4 g/dose) twice weekly or 35 to 40 mg/kg (maximum 3 g/dose) three times per week . One study including 72 adults receiving pyrazinamide …
4. トリメトプリムスルファメトキサゾール：概要trimethoprim sulfamethoxazole an overview [show details]
…TMP-SMX dosing should be altered for patients with renal insufficiency whose creatinine clearance is less than or equal to 30 mL per minute It is generally recommended to provide 50 percent of the dose for… patients in whom adverse reactions occur in approximately 6 to 8 percent of individuals . In comparison, the adverse reaction rate is as high as 25 to 50 percent in HIV-infected…
5. 小児や青年への定期予防接種：概要standard immunizations for children and adolescents overview [show details]
… or use a pacifier). For children <2 years – Administration of sucrose ; the typical dose is 2 mL of 24 percent or 50 percent strength solution administered one to two minutes before injection; glucose …