5-HT2 agonist

出典: meddic

5-HT agonist5-HT1 agonist5-HT3 agonistserotonergic agonistserotonin agonistserotonin receptor agonist

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  • 5-HT1D receptor inhibits renal sympathetic neurotransmission by nitric oxide pathway in anesthetized rats.
  • García-Pedraza JÁ1, García M1, Martín ML1, Morán A2.
  • Vascular pharmacology.Vascul Pharmacol.2015 Sep;72:172-80. doi: 10.1016/j.vph.2015.05.003. Epub 2015 May 21.
  • Although serotonin has been shown to inhibit peripheral sympathetic outflow, serotonin regulation on renal sympathetic outflow has not yet been elucidated. This study investigated which 5-HT receptor subtypes are involved. Wistar rats were anesthetized (sodium pentobarbital; 60mg/kg, i.p.), and prep
  • PMID 26003124
  • An Orally Active Phenylaminotetralin-Chemotype Serotonin 5-HT7 and 5-HT1A Receptor Partial Agonist That Corrects Motor Stereotypy in Mouse Models.
  • Canal CE, Felsing DE, Liu Y, Zhu W, Wood JT, Perry CK, Vemula R, Booth RG.
  • ACS chemical neuroscience.ACS Chem Neurosci.2015 Jul 15;6(7):1259-70. doi: 10.1021/acschemneuro.5b00099. Epub 2015 Jun 8.
  • Stereotypy (e.g., repetitive hand waving) is a key phenotype of autism spectrum disorder, Fragile X and Rett syndromes, and other neuropsychiatric disorders, and its severity correlates with cognitive and attention deficits. There are no effective treatments, however, for stereotypy. Perturbation of
  • PMID 26011730
  • N-Benzyl-5-methoxytryptamines as Potent Serotonin 5-HT2 Receptor Family Agonists and Comparison with a Series of Phenethylamine Analogues.
  • Nichols DE1, Sassano MF1, Halberstadt AL, Klein LM, Brandt SD2, Elliott SP3, Fiedler WJ4.
  • ACS chemical neuroscience.ACS Chem Neurosci.2015 Jul 15;6(7):1165-75. doi: 10.1021/cn500292d. Epub 2015 Jan 21.
  • A series of N-benzylated-5-methoxytryptamine analogues was prepared and investigated, with special emphasis on substituents in the meta position of the benzyl group. A parallel series of several N-benzylated analogues of 2,5-dimethoxy-4-iodophenethylamine (2C-I) also was included for comparison of t
  • PMID 25547199


  • Serotonergic Modulation of Absence-Like Seizures in Groggy Rats: a Novel Rat Model of Absence Epilepsy
  • Ohno Yukihiro,Sofue Nobumasa,Imaoku Takuji,Morishita Eri,Kumafuji Kenta,Sasa Masashi,Serikawa Tadao
  • Journal of Pharmacological Sciences advpub(0), 1008200444, 2010
  • … To explore the role of the serotonergic system in modulating absence seizures, we examined the effects of 5-HT1A and 5-HT2 agonists on the incidence of spike-and-wave discharges (SWD) in Groogy (GRY) rats, a novel rat model of absence-like epilepsy. …
  • NAID 130000302186
  • セロトニン1A受容体アゴニストのSAMマウスへの影響
  • Experimental Animals 59(4), 441-447, 2010
  • … The hallucinogenic chemical 1-[2,5-dimethoxy-4-iodophenyl]-2-aminopropane (DOI), a serotonin receptor 2A (5-HT2AR) agonist, evokes extracellular signal-regulated kinase 1/2 (ERK1/2) signaling and head-twitch behavior. …
  • NAID 130000298604


Methysergide, a congener of methylergonovine, used in treatment of migraine blocks 5-HT2A and 5-HT2C receptors, but sometimes acts as partial agonist, in some preparations. The atypical antipsychotic ...
Conversely, many SSRIs (but not fluoxetine, which is a 5-HT2C antagonist) indirectly stimulate 5-HT2C activity by increasing levels ... Inverse agonists may be required to fully extinguish 5-HT2C constitutive activity, and may prove useful in the ...



リンク元5-HT agonist」「5-HT2刺激薬」「5-HT2作動薬」「serotonin agonist」「serotonergic agonist

5-HT agonist」


5-HT1 agonist5-HT2 agonist5-HT3 agonistserotonergic agentserotonergic agonistserotonin agonistserotonin receptor agonist



5-HT2 agonist



5-HT2 agonist

serotonin agonist」


5-HT agonist5-HT1 agonist5-HT2 agonist5-HT3 agonistserotonergic agentserotonergic agonistserotonin receptor agonist

serotonergic agonist」


5-HT agonist5-HT1 agonist5-HT2 agonist5-HT3 agonistserotonergic agentserotonin agonistserotonin receptor agonist


  [★] 作動薬

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「(biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction」

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「a muscle that contracts while another relaxes; "when bending the elbow the biceps are the agonist"」

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「someone involved in a contest or battle (as in an agon)」



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「the 8th letter of the Roman alphabet」

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「鉛筆の硬度 / 《俗》heroin」