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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/01/25 11:13:41」(JST)

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Overexpression of 5-lipoxygenase and its relation with cell proliferation and angiogenesis in 7,12-dimethylbenz(α)anthracene-induced rat mammary carcinogenesis.

Chatterjee M, Das S, Roy K, Chatterjee M.SourceChemical Carcinogenesis and Chemoprevention Laboratory, Division of Biochemistry, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, India.
Molecular carcinogenesis.Mol Carcinog.2013 May;52(5):359-69. doi: 10.1002/mc.21858. Epub 2011 Dec 28.
The present study was performed to investigate the critical role of 5-lipoxygenase (5-LOX) in 7,12-dimethylbenz(α)anthracene (DMBA)-induced rat mammary inflammation associated carcinogenesis. Female Sprague-Dawley rats at 50 days of age were treated with 7,12-dimethylbenz(α)anthracene (DMBA; 0.5�
PMID 22213124

Fatty acids induce leukotriene C4 synthesis in macrophages in a fatty acid binding protein-dependent manner.

Long EK, Hellberg K, Foncea R, Hertzel AV, Suttles J, Bernlohr DA.SourceDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN 55455 USA.
Biochimica et biophysica acta.Biochim Biophys Acta.2013 Apr 12;1831(7):1199-1207. doi: 10.1016/j.bbalip.2013.04.004. [Epub ahead of print]
Obesity results in increased macrophage recruitment to adipose tissue that promotes a chronic low-grade inflammatory state linked to increased fatty acid efflux from adipocytes. Activated macrophages produce a variety of pro-inflammatory lipids such as leukotriene C4 (LTC4) and 5-, 12-, and 15-hydro
PMID 23583845

Hypoxia suppresses Kv 2.1 channel expression through endogenous 15-hydroxyeicosatetraenoic acid in rat pulmonary artery

New Method for Synthesizing the Intermediates to 5-HETE from Yeast-mediated Reduction Products by Employing Baeyer-Villiger Oxidation with Complete Retention of Enantiomeric Excess(Organic Chemistry)

Yamauchi Satoshi,Kinoshita Yoshihiro,Kinoshita Yoshiro
Bioscience, biotechnology, and biochemistry 67(9), 1959-1969, 2003-09-23
… (R) and (S)-Aldehydes 2, which are intermediates for the synthesis of (5R) and (5S)-HETE, were respectively synthesized from the yeast-mediated reductive products, hydroxy ester 3 and cis-lactone 4, through Baeyer-Villiger oxidation with complete retention of enantiomeric excess. …
NAID 110002694333

Cellular Glutathione Peroxidase as a Predominant Scavenger of Hydroperoxyeicosatetraenoic Acids in Rabbit Alveolar Macrophages

Chiba Nobuyoshi,Imai Hirotaka,Narashima Kazuki [他],ARAI Masayoshi,OSHIMA Gen-ichiro,KUNIMOTO Manabu,NAKAGAWA Yasuhito
Biological & pharmaceutical bulletin 22(10), 1047-1051, 1999-10-15
… The cytosol of rabbit lung alveolar macrophages contains a high amount of peroxidase, which reduces 5-hydroperoxyeicosatetraenoic acid (5-HPETE) to 5-hydroxyeicosatetraenoic acid (5-HETE) in the presence of glutathione. … This peroxidase was purified 69-fold to homogeneity with overall recovery of activity of 18.5%. …
NAID 110003639540

5-Hydroxyeicosatetraenoic acid
	IUPAC name (5S,6E,8Z,11Z,14Z)-5-hydroxyicosa-6,8,11,14-tetraenoic acid
Identifiers
CAS number	70608-72-9
PubChem	5280733
ChemSpider	4444314
ChEBI	CHEBI:28209
ChEMBL	CHEMBL164813
Jmol-3D images	Image 1; Image 2
	SMILES CCCCC/C=C\C/C=C\C/C=C\C=C\[C@H](CCCC(=O)O)O O=C(O)CCC[C@H](O)/C=C/C=C\C\C=C/C\C=C/CCCCC ;
	InChI InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16,19,21H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+/t19-/m1/s1 ; Key: KGIJOOYOSFUGPC-JGKLHWIESA-N InChI=1/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16,19,21H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+/t19-/m1/s1; Key: KGIJOOYOSFUGPC-JGKLHWIEBQ ;
Properties
Molecular formula	C20H32O3
Molar mass	320.47 g/mol
	(verify) (what is: /?); Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
	Infobox references