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Baloch SK1, Ma L, Xu GH, Bai LF, Zhao H, Tang CY, Pang YJ, Yang RW, Wang XM, Lu GH, Yang YH.
Chirality.Chirality.2015 Dec;27(3):274-80. doi: 10.1002/chir.22425. Epub 2015 Feb 6.
In this study, a shikonin ester derivative, compound , was selected to evaluate its anticancer activities and we found that compound exhibited better antitubulin activities against the human HepG2 cell line with an IC50 value of 1.097 μM. Furthermore, the inhibition of tubulin polymerization resu
PMID 25663187

Liquid chromatographic resolution of amino Acid esters of acyclovir including racemic valacyclovir on crown ether-based chiral stationary phases.

Ahn SA1, Hyun MH.
Chirality.Chirality.2015 Dec;27(3):268-73. doi: 10.1002/chir.22424. Epub 2015 Jan 27.
Valacyclovir, a potential prodrug for the treatment of patients with herpes simplex and herpes zoster, and its analogs were resolved on two chiral stationary phases (CSPs) based on (3,3'-diphenyl-1,1'-binaphthyl)-20-crown-6 covalently bonded to silica gel. In order to find out an appropriate mobile
PMID 25626672

Optimization of a Solid-Phase Microextraction method for the Gas Chromatography-Mass Spectrometry analysis of blackberry (Rubus ulmifolius Schott) fruit volatiles.

D'Agostino MF1, Sanz J2, Sanz ML2, Giuffrè AM1, Sicari V1, Soria AC3.
Food chemistry.Food Chem.2015 Jul 1;178:10-7. doi: 10.1016/j.foodchem.2015.01.010. Epub 2015 Jan 10.
A Solid-Phase Microextraction method for the Gas Chromatography-Mass Spectrometry analysis of blackberry (Rubus sp.) volatiles has been fully optimized by means of a Box-Behnken experimental design. The optimized operating conditions (Carboxen/Polydimethylsiloxane fiber coating, 66°C, 20min equilib
PMID 25704677