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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/04/12 08:59:25」(JST)

English Journal

Effect of JBP485 on obstructive jaundice is related to regulation of renal Oat1, Oat3 and Mrp2 expression in ANIT-treated rats.

Liu T, Guo X, Meng Q, Wang C, Liu Q, Sun H, Ma X, Kaku T, Liu K.SourceDepartment of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, China. liutaomedical@qq.com
Peptides.Peptides.2012 Jul;36(1):78-85. Epub 2012 Apr 11.
The objective was to determine whether protective effects of JBP485 on biliary obstruction induced by alpha-naphthylisothiocyanate (ANIT) are mediated by the organic anion transporters Oat1, Oat3 and the multidrug resistance-associated protein Mrp2. The ANIT-induced increases in bilirubin (BIL), ala
PMID 22521734

Gender-specific reduction of hepatic Mrp2 expression by high-fat diet protects female mice from ANIT toxicity.

Kong B, Csanaky IL, Aleksunes LM, Patni M, Chen Q, Ma X, Jaeschke H, Weir S, Broward M, Klaassen CD, Guo GL.SourceDepartment of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Toxicology and applied pharmacology.Toxicol Appl Pharmacol.2012 Jun 1;261(2):189-95. Epub 2012 Apr 11.
Emerging evidence suggests that feeding a high-fat diet (HFD) to rodents affects the expression of genes involved in drug transport. However, gender-specific effects of HFD on drug transport are not known. The multidrug resistance-associated protein 2 (Mrp2, Abcc2) is a transporter highly expressed
PMID 22521610

Semi-automatic liquid chromatographic analysis of pamidronate in urine after derivatization with 1-naphthylisothiocyanate

SPARIDANS Rolf W.,DEN HARTIGH Jan,CREMERS Serge,BEIJNEN Jos H.,VERMEIJ Pieter
Journal of chromatography. B, Biomedical sciences and applications 730(1), 95-99, 1999-06-25
NAID 10024538578

Semi-automatic liquid chromatographic analysis of pamidronate in serum and citrate plasma after derivatization with 1-naphthylisothiocyanate

SPARIDANS Rolf W.,HARTIGH Jan den,BEIJNEN Jos H.,VERMEIJ Pieter
Journal of chromatography. B, Biomedical sciences and applications 705(2), 331-339, 1998-02-13
NAID 10024525880

リンク元	「alpha-naphthylisothiocyanate」「1-ナフチルイソチオシアン酸」

1-Naphthyl isothiocyanate
Names
	Systematic IUPAC name 1-Isothiocyanatonaphthalene
	Other names 1-Naphthylisothiocyanate; α-Naphthyl isothiocyanate; Kesscocide
Identifiers
CAS Number	551-06-4
Abbreviations	ANIT
Beilstein Reference	637868
ChEBI	CHEBI:35455
ChEMBL	ChEMBL1381098
ChemSpider	10609
EC Number	208-990-8
Jmol 3D image	Interactive graph; Interactive graph
MeSH	1-Naphthylisothiocyanate
PubChem	11080
RTECS number	NX9100000
UN number	2811
	InChI InChI=1S/C11H7NS/c13-8-12-11-7-3-5-9-4-1-2-6-10(9)11/h1-7H Key: JBDOSUUXMYMWQH-UHFFFAOYSA-N ; InChI=1/C11H7NS/c13-8-12-11-7-3-5-9-4-1-2-6-10(9)11/h1-7H Key: JBDOSUUXMYMWQH-UHFFFAOYAA ;
	SMILES S=C=Nc1cccc2ccccc12 ; S=C=NC1=CC=CC2=CC=CC=C12 ;
Properties
Chemical formula	C11H7NS
Molar mass	185.24 g·mol−1
Melting point	55 to 57 °C (131 to 135 °F; 328 to 330 K)
Hazards
GHS pictograms
GHS signal word	DANGER
GHS hazard statements	H301, H312, H315, H319, H332, H334, H335
GHS precautionary statements	P261, P280, P301+310, P305+351+338, P342+311
EU classification (DSD)	T
R-phrases	R20/21, R25, R36/37/38, R42
S-phrases	S22, S26, S36/37, S45
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references