UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 女性の生殖能力におよぼすカフェインの影響 the effects of caffeine on reproductive outcomes in women

English Journal

Patients Aged 80 Years or Older are Encountered More Potentially Inappropriate Medication Use.

Mo L, Ding D, Pu SY, Liu QH, Li H, Dong BR, Yang XY, He JH1.
Chinese medical journal.Chin Med J (Engl).2016 5th Jan;129(1):22-27. doi: 10.4103/0366-6999.172558.
BACKGROUND: Polypharmacy and potentially inappropriate medications (PIMs) are prominent prescribing issues in elderly patients. This study was to investigate the different prevalence of PIM use in elderly inpatients between 65-79 years of age and 80 years or older, who were discharged from Geriatric
PMID 26712428

Short-term oxycodone treatment does not affect electrogenic ion transport in isolated mucosa from the human rectosigmoid colon.

Nilsson M1, Brock C1,2, Lykke Poulsen J1, Bindslev N3, Berner Hansen M4,5, Louring Christrup L2, Drewes AM1,6.
Scandinavian journal of gastroenterology.Scand J Gastroenterol.2016 May;51(5):538-47. doi: 10.3109/00365521.2015.1116108. Epub 2015 Nov 26.
Objective Opioid therapy is associated with altered secretion and motility of the gut. The relative contribution of decreased secretion to the development of opioid-induced constipation remains unknown. Materials and methods Twenty-five healthy males were treated with oxycodone for 5 d in a placebo-
PMID 26610166

Stepwise injection potentiometric determination of caffeine in saliva using single-drop microextraction combined with solvent exchange.

Timofeeva I1, Medinskaia K2, Nikolaeva L2, Kirsanov D2, Bulatov A2.
Talanta.Talanta.2016 Apr 1;150:655-60. doi: 10.1016/j.talanta.2016.01.001. Epub 2016 Jan 4.
A flow potentiometric method for determination of caffeine in saliva is suggested. This task is important for non-invasive assessment of drug metabolizing system activity in hepatocytes. In the current study, stepwise injection analysis (SWIA) was successfully combined with single-drop liquid microe
PMID 26838455

Japanese Journal

Involvement of Adenosine A_2 Receptors in the Changes of Tissue Factor-Dependent Coagulant Activity Induced by Polymorphonuclear Leukocytes in Endothelial Cells

Watanabe Tohru,Tokuyama Shogo,Yasuda Masako [他],SASAKI Tadanori,YAMAMOTO Toshinori
The Japanese journal of pharmacology 88(4), 407-413, 2002-04-01
… The increases of the TF activity and adhesion were significantly reduced in a concentration-dependent manner by pretreatment of adenosine (0.1 and 1.0 mM); … an adenosine A1/A2-receptor agonist, CGS-21680 (5, 10 and 50 μM); … 1.0, 10 and 100 nM). … An adenosine A2-receptor antagonist, 3,7-dimethyl-1-(2-propynyl) xanthine (DMPX; …
NAID 10008415103

Intrinsic Factors Involved in the Depression of Neuronal Activity Induced by Temperature Increase in Rat Hippocampal Neurons.

TAKEYA MITSUE
The Kurume Medical Journal 48(4), 295-306, 2001
… The intrinsic factors involved in the temperature-dependent impairment of neuronal activity in hippocampal CA2-CA1 regions were investigated using optical recording techniques. … At 32°C, stimulation of the Schaffer collaterals in the hippocampal CA2 region evoked depolarizing optical responses that spread toward the CA1 region. …
NAID 130000882114

<Abstract of Published Report>A High Chemical Reactivity of 5-Azidouracils and Its Synthetic Application : Novel Synthesis of 8-Substituted 1,3-Dimethylxanthine Derivatives.

HIROTA Kosaku/SAKO Magoichi/SAJIKI Hironao
岐阜藥科大學紀要 = The annual proceedings of Gifu College of Pharmacy 47, 58, 1998-06-30
NAID 120005563119

Related Pictures

Bronchodilatateur xanthique Cyclopentyl-1,3-dimethylxanthine.png Chemical name theophylline: 1,3-dimethylxanthine theobromine Figure US20130129641A1-20130523-C00001 Dimethylxanthine; 3,7-Dihydro-1,3 of 1 3 dimethylxanthine theophylline 3