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1. オピオイド使用障害：疫学、薬理学、臨床症状、経過、スクリーニング、評価、および診断opioid use disorder epidemiology pharmacology clinical manifestations course screening assessment and diagnosis [show details]
… Opioids, used medically for pain relief, have analgesic and central nervous system depressant effects as well as the potential to cause euphoria. Opioid use disorder (OUD) can involve misuse of prescribed …
2. 成人における薬物中毒への一般的アプローチgeneral approach to drug poisoning in adults [show details]
…involved were analgesics (15.2 percent), antidepressants (11.4 percent), and opioids (10.9 percent) . Reviews of self-poisoning cases in the United Kingdom and Spain found that analgesics,… 2008 and 2011, there were an estimated 1.1 million annual emergency department visits related to drug poisoning, or 35.4 visits per 10,000 persons; 24.5 percent of these patients required hospital admission …
3. 処方剤の誤用：疫学、予防、同定、およびマネージメントprescription drug misuse epidemiology prevention identification and management [show details]
…of opioid analgesics for pain management since the 1990s, associated morbidity and mortality have risen markedly. There were over 63,600 deaths in the United States in 2016 due to drug overdose; approximately …
4. 子供の疼痛：疼痛評価へのアプローチとマネージメント原則の概要pain in children approach to pain assessment and overview of management principles [show details]
…with nonopioid analgesics Nonopioid analgesics include acetaminophen and NSAIDs. Aspirin use has declined since the 1970s because of its association with Reye syndrome. Nonopioid analgesics are effective …
5. 成人における非がん性慢性疼痛の薬物的管理pharmacologic management of chronic non cancer pain in adults [show details]
… potent analgesic, but analgesic response has not been directly compared among drugs in this class. Of all antidepressants, duloxetine has the largest evidence base to support analgesic efficacy,… 2019 to 2020 data from the State Unintentional Drug Overdose Reporting System (SUDORS) in 23 states and the District of Columbia,…