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1. 造血幹細胞の概要overview of hematopoietic stem cells [show details]
… transcription factors are essential for the development of the different cell lineages because they dictate the synthesis of lineage specific proteins such as cell surface growth factor receptors .… extrinsic factors (such as leukopenia or anemia) in the regulation of stem cell levels is uncertain . The expression of transcription factors and the critical genes regulated by them during hematopoiesis are…
2. 骨髄造血の制御regulation of myelopoiesis [show details]
…successive combinations of transcription factors that in turn dictate the expression of adhesion and hematopoietic growth factor receptors (HGFRs): Adhesion receptors play an important role in the localization …
3. トロンボポエチンの生物学および生理学biology and physiology of thrombopoietin [show details]
… portion of a membrane protein which had all the characteristics of a new hematopoietic growth factor receptor . When the full-length homolog (c-Mpl) was cloned , its mRNA was found to be present at significant …
4. 未確定の潜在能をもつクローン性造血（CHIP）とクローン性造血の関連疾患clonal hematopoiesis of indeterminate potential chip and related disorders of clonal hematopoiesis [show details]
… include: Clonal hematopoiesis of indeterminate potential (CHIP) Clonal cytopenia of undetermined significance (CCUS) Aging-related clonal hematopoiesis (ARCH) CHIP,… PPM1D, and BCORL1 . These genes reflect a broad array of cellular functions, including transcription factors, chromatin modifiers, DNA repair, ribonucleoprotein binding proteins, spliceosome components, signal … associated with Hispanic ethnicity, African ancestry, and germline variants of MPL (thrombopoietin receptor), telomere-associated genes, and genes of uncertain significance (FRA10B, TM2D3) . In addition …
5. 赤血球産生調節regulation of erythropoiesis [show details]
… their receptors have provided insights into the role of these factors during hematopoiesis. Erythropoietin (EPO) is essential for the terminal maturation of erythroid cells . Its major effect appears to …

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★リンクテーブル★

リンク元	「コロニー刺激因子受容体」
関連記事	「受容体」「造血」「受容」「体」「因子」

「コロニー刺激因子受容体」

　　[★]

英: colony-stimulating factor receptor、CSF receptor、CSFR
同: CSF受容体 CSF receptor、造血因子受容体 hemopoietic factor receptor
関: コロニー刺激因子レセプター

「受容体」

　　[★]

英: receptor
同: レセプター、リセプター
関

図：GOO.27

種類

イオンチャネル連結型受容体 (イオンチャネル型受容体)
酵素連結型受容体
Gタンパク質共役型受容体 (代謝調節型受容体)

First Aid FOR THE USMLE STEP 1 2006 p.199

一般的作動薬	受容体	G protein subunit	作用
アドレナリンノルアドレナリン	α1	Gq	血管平滑筋収縮
	α2	Gi	中枢交感神経抑制、インスリン放出抑制
	β1	Gs	心拍数増加、収縮力増加、レニン放出、脂肪分解
	β2		骨格筋筋弛緩、内臓平滑筋弛緩、気道平滑筋弛緩、グリコーゲン放出
	β3		肥満細胞脂質分解亢進
アセチルコリン	M1	Gq	中枢神経
	M2	Gi	心拍数低下
	M3	Gq	外分泌腺分泌亢進
ドーパミン	D1	Gs	腎臓平滑筋弛緩
ドーパミン	D2	Gi	神経伝達物質放出を調節
ヒスタミン	H1	Gq	鼻、器官粘膜分泌、細気管支収縮、かゆみ、痛み
ヒスタミン	H2	Gs	胃酸分泌
バソプレシン	V1	Gq	血管平滑筋収縮
バソプレシン	V2	Gs	腎集合管で水の透過性亢進