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1. 骨壊死症の臨床症状と診断（無血管性骨壊死症）clinical manifestations and diagnosis of osteonecrosis avascular necrosis of bone [show details]
… the pathognomonic crescent sign (subchondral radiolucency ) is evidence of subchondral collapse.… factor (VEGF), promote angiogenesis . However, the angiogenesis is often impaired, resulting in demineralization, followed by trabecular thinning, and, later, by collapse . The histopathologic finding of bone …
2. 離断性骨軟骨炎（OCD）：臨床症状、評価および診断osteochondritis dissecans ocd clinical manifestations evaluation and diagnosis [show details]
… chondromalacia. The necrotic bone is then replaced by subchondral trabeculae or cartilage . As the lesion progresses, focal areas of demineralization and repeated shear forces cause detachment of the bone …
3. 関節リウマチの全身および非関節症状の概要overview of the systemic and nonarticular manifestations of rheumatoid arthritis [show details]
… the subchondral cysts that develop when high intraarticular pressures force synovial fluid through breaks in the subchondral plate in patients who… Periarticular – Demineralization in a periarticular distribution is characteristic…
4. 糖尿病性神経性関節症diabetic neuroarthropathy [show details]
… Non-contrast MRI in stage 0 Charcot neuroarthropathy typically shows subchondral bone marrow edema with or without microfracture .… Radiographs are usually normal initially but then may show patchy demineralization.…
5. 細菌性関節炎：乳児や小児における臨床的特徴および診断bacterial arthritis clinical features and diagnosis in infants and children [show details]
… suggesting adjacent osteomyelitis; Erosion of subchondral bone (present two to four weeks after the onset)… since bone demineralization or destruction takes a minimum of a week to become…