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1. 成人における頭蓋内圧亢進の評価およびマネージメントevaluation and management of elevated intracranial pressure in adults [show details]
…maintained at a relatively constant level by cerebrovascular autoregulation of CVR over a wide range of CPP (50 to 100 mmHg) . However, autoregulation of CVR can become dysfunctional in certain pathologic states …
2. 成人における中等度～重症の高血圧性網膜症および高血圧性脳症moderate to severe hypertensive retinopathy and hypertensive encephalopathy in adults [show details]
…transmitted to the smaller, more distal vessels . With increasingly severe hypertension, however, autoregulation eventually fails . The ensuing rise in pressure in the arterioles and capillaries leads to acute …
3. 敗血症の病態生理pathophysiology of sepsis [show details]
…and an altered rate of apoptosis (programmed cell death). Significant derangement in metabolic autoregulation, the process that matches oxygen availability to changing tissue oxygen needs, is typical of …
4. 中度と重度の急性外傷性脳損傷のマネージメントmanagement of acute moderate and severe traumatic brain injury [show details]
…Through autoregulation, the normal cerebral vasculature maintains an adequate cerebral blood flow (CBF) across a wide range (50 to 150 mmHg) of mean arterial pressure (MAP). Cerebral autoregulation is disrupted …
5. 高血圧におけるACE阻害剤の腎への効果renal effects of ace inhibitors in hypertension [show details]
…hypertension is related both to the glomerular actions of angiotensin II and the mechanism of autoregulation of the glomerular filtration rate (GFR) . Angiotensin II constricts both the afferent (preglomerular) …