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1. 自己炎症疾患：概要the autoinflammatory diseases an overview [show details]
…antigen-specific arm of the immune response, referred to as adaptive immunity, is based upon learned self/nonself discrimination mediated by selective expansion of T and B cell clones in which genetic recombination …
2. 腫瘍壊死因子受容体-1関連周期性発熱症候群（TRAPS）tumor necrosis factor receptor 1 associated periodic syndrome traps [show details]
… Many well-known disorders of immune excess result from a failure of self/nonself discrimination by T and B cells, the effector cells of the adaptive arm of the immune system. A second category of immune-mediated…
3. 感染症を繰り返す成人に対するアプローチapproach to the adult with recurrent infections [show details]
…higher risk of malignancies. A fundamental function of the immune system is to distinguish "self" from "nonself." This capacity is critical not only for defense against invading micro-organisms but also …
4. 母体 - 胎児接点の免疫immunology of the maternal fetal interface [show details]
…the mother and the semi-allograft that is the fetus/placenta expressing both maternal (self) and paternal (nonself) genes . Cytotoxic adaptive immune responses are diminished, bypassed, or even abrogated…
5. インスリンに対する過敏症反応hypersensitivity reactions to insulins [show details]
…detemir, and degludec) can induce allergic reactions. The antigenic epitope may be a nonself-epitope, an altered self-epitope, or an epitope generated by alternate protein folding that can occur during…