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1. 心房細動の機序mechanisms of atrial fibrillation [show details]
… with AF also display increased atrial fibrous tissue content, along with increased expression of collagen I and III , as well as up-regulation of MMP-2 protein, and down-regulation of the tissue inhibitor … while exercise can be protective against atrial fibrillation, endurance athletics may be a cause for atrial fibrillation .…
2. 変形性関節症の病因pathogenesis of osteoarthritis [show details]
…at the surface of the articular cartilage with fibrillation in focal regions that experience maximal loading. The cartilage initially swells as the collagen network loosens allowing the hydrophilic proteoglycans …
3. 外傷性末梢神経障害traumatic peripheral neuropathies [show details]
… the natural resting tension permitted by the amount of the elastin and collagen present in the perineural layer of nerve allows for… no spontaneous activity such as fibrillation potentials or positive waves is expected.…
4. 駆出率低下を伴う心不全における薬理療法：作用機序pharmacologic therapy of heart failure with reduced ejection fraction mechanisms of action [show details]
… Patients with higher serum concentrations of markers of collagen synthesis (procollagen type I carboxy-terminal peptide,… Attenuation of atrial remodeling and reduced incidence of atrial fibrillation .…
5. 肥大型心筋症：自然経過および予後hypertrophic cardiomyopathy natural history and prognosis [show details]
… The mechanisms leading to increased collagen matrix in HCM are not well defined but may be mediated by angiotensin II,… atrial fibrillation due to the high observed risk of stroke. Similar findings were reported from a Japanese cohort of 593 patients with HCM (including 431 without known atrial fibrillation at baseline)…