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1. 腎機能障害患者の炎症inflammation in patients with kidney function impairment [show details]
…high-flux membranes. Nevertheless, this finding does not necessarily refute a role of dialysis membranes in the development of chronic inflammation in patients with ESKD, since the membrane effect on survival …
2. 心血管疾患の明確な危険因子の概要overview of established risk factors for cardiovascular disease [show details]
… of the IL6R gene encoding IL-6R, is associated with reduced membrane-bound IL-6R, resulting in decreased IL-6R signalling and less inflammation . Two large meta-analyses have confirmed the crucial role played …
3. 補体系の概要および臨床的評価overview and clinical assessment of the complement system [show details]
… target and then the assembly of the membrane attack complex (MAC). The MAC perturbs cell membrane integrity and in organisms such as gram-negative bacteria,… "anaphylatoxins," bind to their respective receptors on cells to initiate inflammation and vasodilation that in turn activate many cell types .…
4. 痛風の病態生理pathophysiology of gout [show details]
… feedback loop of inflammation. Once in the inflamed joint, some neutrophils are subject to either crystal phagocytosis-induced degranulation or direct crystal lysis of lysosomal or cell membranes , with the …
5. 関節リウマチにおける冠動脈疾患：病因、危険因子、臨床症状、および診断上の注意点coronary artery disease in rheumatoid arthritis pathogenesis risk factors clinical manifestations and diagnostic implications [show details]
…atherosclerotic plaque; these abnormalities are similar to those encountered in the inflamed synovial membrane . Inflammation may worsen insulin resistance and impair pancreatic beta cell function . These metabolic …