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1. 腹膜透析での溶質除去不足inadequate solute clearance in peritoneal dialysis [show details]
…Kt/Vurea in patients receiving peritoneal dialysis is discussed elsewhere. We perform a peritoneal equilibration test (PET) if the peritoneal Kt/Vurea (ie, peritoneal clearance) is decreased from baseline …
2. 持続的腹膜透析における溶質クリアランスの測定：Kt/Vとクレアチニンクリアランスmeasurement of solute clearance in continuous peritoneal dialysis kt v and creatinine clearance [show details]
…decreases the total urea clearance. Since both creatinine and urea are surrogate solutes, CCr overestimates and urea clearance underestimates renal solute clearance. Peritoneal clearance of solute is primarily …
3. 腹膜透析における溶質クリアランスおよび限外濾過の機序mechanisms of solute clearance and ultrafiltration in peritoneal dialysis [show details]
…peritoneum. The concept of mass transfer area coefficient (MTAC) represents the theoretical maximal peritoneal clearance by diffusion at time 0 (ie, before any solute transport has occurred). At this time, the concentration …
4. 腹膜平衡試験peritoneal equilibration test [show details]
… The effective peritoneal dialysis dose is customarily measured by calculating the clearance of creatinine, which is the product of the D/P creatinine and the drain volume: Solute clearance and UF vary with …
5. 腹膜透析の処方prescribing peritoneal dialysis [show details]
…or >2.0 . All patients had residual kidney urea clearance <1.0, and the clearance provided by residual kidney function was added to the peritoneal clearance. There were no differences among groups in survival …

「クリアランス」

　　[★]

英: clearance
同: 清掃値、浄化値

定義

1. ある物質について、単位時間あたりどれだけの量の血液をきれいにできるか。
2. ある物質が排泄されるために必要な単位時間あたりの血漿量
3. ある物質が単位時間に腎によって完全に除去(清掃)される血漿の量 (生理学実習1 実習テキスト p.4,SP.777-778)
4. it is defined as the rate of elimination of the drug from the body relative to the concentration of the drug in plasma

(PPC.42) [(amount/time)/(amount/volume)]

5. clearance is the rate at which plasma would have to be cleared of the drug to account for the observed kinetics of change of the total amount of drug in the body, assuming that all the drug in the body is present at the same concentration as that in the plasma.(PPC.42)