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1. 成人のクローン病の治療：腫瘍壊死因子a阻害薬の用法・用量とモニタリングtreatment of crohn disease in adults dosing and monitoring of tumor necrosis factor alpha inhibitors [show details]
… on maintenance dosing can be managed by escalating the dose . Additionally, individuals who achieve an incomplete response can be managed in a similar fashion. Dose escalation can be… monoclonal antibodies directed against tumor necrosis factor (TNF)-alpha. The basis for their use in Crohn disease is that tumor necrosis factor (TNF)-alpha has… higher infliximab trough levels were associated with healing of perianal fistula related to Crohn disease ,…
2. 成人の潰瘍性大腸炎治療に用いる生物学的製剤や低分子医薬品の用量およびモニタリングの概要overview of dosing and monitoring of biologic agents and small molecules for treating ulcerative colitis in adults [show details]
… response while on maintenance dosing and who are candidates for dose escalation, options include increasing the maintenance dose to 100 mg every four weeks,… chronic inflammatory disease of the colon characterized by bloody diarrhea. Biologic agents, including tumor necrosis factor-alpha inhibitors (eg, infliximab) and anti-integrin antibodies (vedolizumab), and …
3. 創傷の治癒遅延に関係する危険因子と合併症risk factors for impaired wound healing and wound complications [show details]
… suspected within the stages of wound healing. Radiation therapy has evolved as a powerful tool for tumor control as a sole therapy or administered adjunctively.… include apoptosis (cell death) with low doses of radiation or outright tissue necrosis with higher doses of radiation.…
4. 遺伝性低リン血症性くる病と腫瘍誘発性骨軟化症hereditary hypophosphatemic rickets and tumor induced osteomalacia [show details]
… complete tumor resection, which leads to prompt reversal of the biochemical abnormalities and healing of the bone disease over a period of 6 to 12 weeks . However, if the tumor is not localized… procedure to ensure optimal healing of the bone and secure placement of hardware. For adults with XLH, burosumab is dosed starting at approximately 1 mg/kg…
5. 転移性の高分化型膵管系神経内分泌（カルチノイド）腫瘍：腫瘍増殖およびホルモン過剰分泌による症状を管理するための全身治療の選択肢metastatic well differentiated pancreatic neuroendocrine tumors systemic therapy options to control tumor growth and symptoms of hormone hypersecretion [show details]
… months of study entry, with visible tumor uptake on pretreatment SSTR scintigraphy . After the initial dose, additional treatment cycles were withheld if there was tumor progression or permanent toxicity; …