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1. 家族性地中海熱のマネージメントmanagement of familial mediterranean fever [show details]
…side effects may benefit from divided doses. Colchicine-resistant FMF – Patients with FMF who still experience frequent attacks despite the maximal tolerable dose of colchicine (up to 3 mg daily in adults …
2. 肝疾患を有する患者における化学療法による肝毒性および用量調整：従来の細胞障害性薬物chemotherapy hepatotoxicity and dose modification in patients with liver disease conventional cytotoxic agents [show details]
…liver is itself hepatotoxic, otherwise tolerable doses of radiation therapy to the right upper quadrant can induce severe hepatic injury when combined with systemic doses of normally nonhepatotoxic chemotherapeutic …
3. 蛋白漏出性胃腸症protein losing gastroenteropathy [show details]
…oils may exceed tolerable levels. Excessive intake of MCTs can cause gastrointestinal distress, including nausea and diarrhea, so starting at a low dose and titrating up to a tolerable provision is advised …
4. 小児や青年の不安障害への薬物療法pharmacotherapy for anxiety disorders in children and adolescents [show details]
…initial therapeutic dose. If symptoms do not remit after six to eight weeks, the dose is increased incrementally and tested, until the maximum dose is reached or side effects are not tolerable. Antidepressants …
5. 分化型甲状腺癌：放射性ヨード治療differentiated thyroid cancer radioiodine treatment [show details]
…ascertain their safety. Empiric dosing regimens may exceed the maximum tolerable doses as predicted by dosimetry, especially in older adults . As an example, in one study, a dose of 200 mCi (7.5 GBq) exceeded …