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1. マントル細胞リンパ腫の病理学pathobiology of mantle cell lymphoma [show details]
… (BTK) inhibitors such as ibrutinib have shown excellent, durable single agent activity in MCL . BTK functions downstream of the membrane-bound B cell receptor (BCR) and links constitutive BCR signaling to …
2. 有毛細胞白血病の治療treatment of hairy cell leukemia [show details]
… cytotoxic to both resting and dividing cells. Both drugs induce durable complete remissions (CR) in the overwhelming majority of patients with HCL. Equally high rates of durable CRs are achieved with these two …
3. 局所療法が無効な進行性基底細胞癌および皮膚扁平上皮癌の全身療法systemic treatment of advanced basal cell and cutaneous squamous cell carcinomas not amenable to local therapies [show details]
… percent) responses . A majority (79 percent) of patients maintained durable responses lasting six months or longer. Metastatic basal cell carcinoma – Among the 28 patients with metastatic BCC, objective …
4. 原発性皮膚T細胞リンパ腫（まれな亜型）primary cutaneous t cell lymphomas rare subtypes [show details]
… entities, such as subcutaneous panniculitis-like T cell lymphoma; extranodal natural killer/T cell lymphoma, nasal type; primary cutaneous peripheral T cell lymphoma (PTCL), not otherwise specified; and rare …
5. 多発性骨髄腫：同種造血細胞移植multiple myeloma use of allogeneic hematopoietic cell transplantation [show details]
… either malignant cells at three months or no malignant cells at three months reverting to malignant cells at six months) had a five-year survival of 54 percent.… but in this setting the risks are higher and the probability of a durable remission is low.…

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