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1. ペリツェウス・メルツバッハー病pelizaeus merzbacher disease [show details]
…abnormalities. In normal full-term infants, myelination is usually evident on MRI in the pons and cerebellum, and by the age of three months, normal infants show myelination in the posterior limb of the internal …
2. シェーグレン・ラルソン症候群sjogren larsson syndrome [show details]
…including leukoencephalopathy . In SLS, myelination is delayed, and some patients have unmyelinated subcortical association fibers, suggesting that the process of myelination does not reach completion in these …
3. 視神経の先天性および後天性異常congenital anomalies and acquired abnormalities of the optic nerve [show details]
… High myopia and amblyopia can occur when the myelination is severe . Myelination of the nerve fiber layer may progress after birth ,… fibrous tissue that represents persistence of the normal hyaloid vascular system.…
4. シャルコー・マリー・トゥース病：マネージメントおよび予後charcot marie tooth disease management and prognosis [show details]
…resulted in a more progressive neuropathy . Ascorbic acid (vitamin C), which is known to promote myelination, appeared promising in an animal model of CMT1A . Ascorbic acid therapy reduced the expression …
5. アスパルトアシラーゼ欠乏症（カナバン病）aspartoacylase deficiency canavan disease [show details]
…conformational stability, which result in diminished or nearly absent enzymatic activity . Abnormal myelination, with associated prominence of swollen, vacuolated astrocytes, is a fundamental hallmark of aspartoacylase …