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1. 非ステロイド性抗炎症剤（NSAIDs）（アスピリンを含む）：胃十二指腸障害の病因nsaids including aspirin pathogenesis of gastroduodenal toxicity [show details]
…surgery for an ulcer complication. The most subtle change is disruption of mucosal barrier function, manifest as increased mucosal permeability to hydrogen ions (which then diffuse more rapidly from the lumen …
2. 健常者および疾患を有する患者における腸内細菌叢の分布spatial organization of intestinal microbiota in health and disease [show details]
…corresponding to an agarose concentrations of 0.7 percent. Although the effects of detergents on the mucosal barrier in humans are unknown, in the mouse model, the addition of DSS to food induces acute colitis …
3. 資源国に居住する小児の慢性下痢の原因に関する概要overview of the causes of chronic diarrhea in children in resource rich settings [show details]
…include anatomic defects and heritable disorders of immune regulation, macronutrient digestion, mucosal barrier function, and transport ; these disorders are discussed in a separate topic review. The UpToDate …
4. 嚢炎：疫学、病因、臨床症状、診断pouchitis epidemiology pathogenesis clinical features and diagnosis [show details]
…glycoproteins may be more susceptible to enzymatic degradation by microbiota, leading to the breach of mucosal barrier function and subsequent pouchitis . Prior to the onset of histologic inflammation, pouches …
5. 化学療法に関連した経口毒性oral toxicity associated with chemotherapy [show details]
…creates a physical barrier to pathogens and provides clearance of adhering microorganisms through the regular sloughing of surface epithelial cells . Breakdown of the mucosal barrier predisposes to bacterial …