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1. ロッキー山紅斑熱リケッチア感染の生物学biology of rickettsia rickettsii infection [show details]
…ubiquitination of Ku70. Endothelial cellular processes are normally modulated by the ubiquitous second messenger cAMP, which in turn acts upon the cAMP receptors protein kinase A and an exchange protein called Epac …
2. パーキンソン病の運動症状の日内変動とジスキネジアの医療管理medical management of motor fluctuations and dyskinesia in parkinson disease [show details]
…in which dyskinesia peaks twice after each dose, first when patients turn "on" and again when they begin to turn "off" . In the second phase, dyskinesia (often large-amplitude movements involving the legs) …
3. 淋菌感染の疫学および病因epidemiology and pathogenesis of neisseria gonorrhoeae infection [show details]
… the acquisition of gonococcal infection implies risky sexual behavior that is in turn a risk factor for HIV infection. Second, the presence of gonococcal infection appears to facilitate both the transmission…
4. 薬理ゲノム学の概要overview of pharmacogenomics [show details]
…is induction or inhibition of CYP3A4 caused by administration of a drug, which in turn alters the metabolism of a second drug. This subject is discussed in detail separately. More applicable to the field …
5. 輸血関連急性肺障害（TRALI）transfusion related acute lung injury trali [show details]
… to HLA Class II antigens on monocytes, causing release of cytokines that in turn activate primed neutrophils . When the second hit for neutrophil activation is a BRM rather than an antibody, the BRM is …