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1. アポトーシスと自己免疫疾患apoptosis and autoimmune disease [show details]
… that lead to apoptosis are regulated by several proteins that bind to death receptors, adaptors, or caspases to modulate their function. One of the hallmarks of apoptosis is that cells… caspase-3) which directly cleave structural proteins (eg, nuclear lamins and cytoskeletal gelsolins) and enzymes, such as the inhibitor of caspase-activated DNase (ICAD).…
2. 敗血症の病態生理pathophysiology of sepsis [show details]
…(lipopolysaccharide binding protein, bactericidal permeability increasing protein), mannose-binding lectin, heat shock protein 70, angiotensin I-converting enzyme, plasminogen activator inhibitor,… Several animal experiments show that inhibiting apoptosis protects against organ dysfunction and lethality .…
3. 膀胱癌の分子生物学molecular biology of bladder cancer [show details]
… In combination with other cell-cycle proteins, RB expression has also been noted to be prognostic . CDK inhibitors such as p21,… checkpoint proteins, which are molecules that impede immune function, thereby allowing tumor cells to grow and proliferate unregulated. By binding to the associated programmed cell death protein 1 (PD-1)…
4. 心臓の再灌流障害reperfusion injury of the heart [show details]
… Delcasertib is an inhibitor of the delta isoform of protein kinase C. Protein kinase C isoenzymes modulate myocardial protection.…leading to apoptosis not only within the infarct area, but also in the border zone . Apoptosis, or programmed cell death, has a number of features that distinguish it from necrosis: Apoptosis can occur…
5. 多発性骨髄腫：病理生物学的特徴multiple myeloma pathobiology [show details]
… death-associated protein (DAP) kinase . DAP-kinase regulates apoptosis induced by interferon alfa, and may affect overall prognosis. In normal B cells, binding of Fas to Fas ligand (FasL) induces apoptosis .… of cyclin proteins in MM: Overexpression of cyclin D1, cyclin D2, or cyclin D3 through translocations with the immunoglobulin heavy chain (IgH) locus. Loss of cyclin D kinase inhibitors (CdkI;…

「蛋白質」

英: protein
同: タンパク質、タンパク、蛋白、プロテイン
関: アミノ酸、ポリペプチド

L-アミノ酸が重合してできた高分子化合物であり、生物の重要な構成成分のひとつである。

食事摂取基準

年齢		男性				女性
年齢		推定平均必要量	推奨量	目安量	耐容上限量	推定平均必要量	推奨量	目安量	耐容上限量
0～5（月）		―	―	10	―	―	―	10	―
6～8（月）		―	―	15	―	―	―	15	―
6～11（月）		―	―	―	―	―	―	―	―
9～11（月）		―	―	25	―	―	―	25	―
1～2（歳）		15	20	―	―	15	20	―	―
3～5（歳）		20	25	―	―	20	25	―	―
6～7（歳）		25	30	―	―	25	30	―	―
8～9（歳）		30	40	―	―	30	40	―	―
10～11（歳）		40	45	―	―	35	45	―	―
12～14（歳）		45	60	―	―	45	55	―	―
15～17（歳）		50	60	―	―	45	55	―	―
18～29（歳）		50	60	―	―	40	50	―	―
30～49（歳）		50	60	―	―	40	50	―	―
50～69（歳）		50	60	―	―	40	50	―	―
70以上（歳）		50	60	―	―	40	50	―	―
妊婦（付加量）	初期					＋ 0	＋ 0	―	―
	中期					＋ 5	＋ 5	―	―
	末期					＋ 20	＋ 25	―	―
授乳婦（付加量）						＋ 15	＋ 20	―	―