UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 脳性麻痺：痙縮、ジストニア、脳性麻痺に伴う筋骨格系疾患の治療cerebral palsy treatment of spasticity dystonia and associated orthopedic issues [show details]
… diazepam) are widely used to treat spasticity. Small randomized trials in children with spastic CP have demonstrated that diazepam reduces hypertonia,… including difficulty swallowing or breathing, have been reported as rare complications . Providers should be alert for the potential of systemic effects, including dysphagia,…
2. 筋萎縮性側索硬化症の症状に基づくマネージメントsymptom based management of amyotrophic lateral sclerosis [show details]
… Weight loss is common in ALS and may be due to dysphagia, poor appetite, or difficulty self-feeding due to arm weakness. Dysphagia increases the risk for insufficient… Spastic muscle tone may be useful to help patients maintain antigravity power as muscle weakness progresses. However, excess spasticity can be uncomfortable…
3. 緩和ケアにおける嚥下障害および誤嚥：定義、影響、病態生理、および病因swallowing disorders and aspiration in palliative care definition consequences pathophysiology and etiology [show details]
… may be contributing to or causing dysphagia. Many pharmacologic agents can create or worsen dysphagia. There are approximately 160 known medications that list dysphagia as a potential adverse side effect …
4. 成人の嚥下障害の評価法approach to the evaluation of dysphagia in adults [show details]
… normal in a patient with dysphagia to solids and/or liquids, further evaluation with esophageal manometry and/or barium esophagram should be obtained. Hypertensive or spastic motility disorders: Esophageal …
5. 脳性麻痺：マネージメントおよび予後の概要cerebral palsy overview of management and prognosis [show details]
… rhizotomy is an option for some patients with spastic diplegia. Placement of an intrathecal baclofen pump is generally reserved for patients with severe spasticity refractory to medical management. These interventions …

Related Links

傍シルビウス裂症候群

１．概要シルビウス裂周辺の異常脳回（多くは多小脳回）もしくは機能異常により、構語障害・嚥下困難・上肢優位の痙性麻痺をきたし、知能障害やてんかん発作・高次脳機能障害を併発する難治性疾患である。1993 年にKuznieckyらが初報告した。まれな疾患であり、国内では多くが症例報告でまとまったデータはない。近年、原因遺伝子の報告や、脳磁図によるてんかん焦点の解析と外科治療など、進歩が著しい。

副作用モニター情報〈522〉ボトックス注による嚥下（えんげ ...

投与44日後：固形物摂取可能. なお、本症例は、7年前にボトックス注を投与した際にも嚥下障害を認めていたことが後にわかっており、2度目の副作用発生です。. 添付文書では、けいれん性発声障害へのボトックス注使用による嚥下障害の副作用発生率は40.9％（9／22例）、PMDAには2004～2018年までに嚥下障害の副作用（全ての適応症を含む）が22件、誤嚥性肺炎 ...