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1. 癌の既往はないがBRCA1/2遺伝子変異がある女性の発症リスクとリスク管理cancer risks and management of brca1 2 carriers without cancer [show details]
… Additionally, although BRCA carriers are at a high risk of breast cancer, they cannot be equated with women who have been diagnosed with breast cancer. For carriers with symptomatic vaginal atrophy, nonhormonal …
2. デュシェンヌ型およびベッカー型筋ジストロフィー：臨床的特徴および診断duchenne and becker muscular dystrophy clinical features and diagnosis [show details]
…boy) should be used to determine carrier status wherever possible. The elevations are usually mild (up to three times the upper limit of normal). In symptomatic carriers, however, the CK levels may be much …
3. 腸チフスおよびバラチフスの疫学、微生物学的特性、臨床症状、診断epidemiology microbiology clinical manifestations and diagnosis of enteric typhoid and paratyphoid fever [show details]
…arteritis or chorioamnionitis in HIV-infected patients. In general, chronic carriers do not develop recurrent symptomatic disease. They appear to reach an immunologic equilibrium in which they are chronically …
4. 皮質下梗塞および白質脳症を伴う常染色体優性脳動脈症（CADASIL）cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy cadasil [show details]
…deficits are the second most frequent feature, observed in about 60 percent of symptomatic patients with CADASIL. Among carriers of pathogenic NOTCH3 variants, approximately 75 percent eventually develop dementia …
5. 嚢虫症：疫学、感染、予防cysticercosis epidemiology transmission and prevention [show details]
…with cysticercosis are tapeworm carriers, but most individuals with intestinal tapeworm infection do not develop symptomatic cysticercosis . However, human tapeworm carriers are at risk for fecal-oral autoinoculation …

Japanese Journal

Clostridioides difficileの微生物学的特徴と病態 (今月の特集 Clostridioides difficile感染症 : 近年の話題)

森永芳智
臨床検査 = Journal of clinical laboratory medicine 64(3), 214-219, 2020-03
NAID 40022168995

症例報告腸チフスの無症候性キャリアの治療中に発症した乳児例

伊藤卓冬,梶田光春,鈴木大路,辻元基,西田大恭,生駒雅信
日本小児科学会雑誌 = The journal of the Japan Pediatric Society 123(8), 1278-1282, 2019-08
NAID 40021994570

HTLV-1関連脊髄症（HAM）

山野嘉久
ウイルス 69(1), 29-36, 2019
… HTLV-1関連脊髄症（HAM）は，ヒトT細胞白血病ウイルス1型（HTLV-1）の感染者の一部に発症する神経難病である．HTLV-1はTリンパ球を宿主細胞とするレトロウイルスで，感染者の多くは無症候性キャリアのまま生涯をおくるが，感染者の一部にHAMや成人T細胞白血病リンパ腫（Adult T cell leukemia/lymphoma : ATL）などの重篤な疾患を起こすという特徴をもつ．本稿では，HTLV-1のウイルス学的特徴やHAMの疾患概要，最近のHAMの分子レベ …
NAID 130007905324