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1. 小児や青年のホジキンリンパ腫の概要overview of hodgkin lymphoma in children and adolescents [show details]
… characteristic cellular infiltrate. The biology of HRS cells and their role in HL are discussed separately. Epstein-Barr virus (EBV) infection is associated with many, but not all cases of HL. When EBV is …
2. 成人の古典的ホジキンリンパ腫サバイバーへのアプローチapproach to the adult survivor of classic hodgkin lymphoma [show details]
…among HL survivors and may not be apparent until years after treatment. Classic HL constitutes the large majority of HL, and includes the following pathologic categories: nodular sclerosis HL, mixed cellularity… impact of late effects on HL survivors. Second malignancies are the leading cause of death in long-term survivors of HL. Types of cancer and the time course…
3. 成人に生じる古典型ホジキンリンパ腫の治療の概要overview of the treatment of classic hodgkin lymphoma in adults [show details]
… of patients with Hodgkin lymphoma (HL, formerly called Hodgkin disease) is primarily guided by the clinical stage of disease as determined… but is also important for the comparison of results obtained with different types of treatment in different studies.…
4. 成人に生じる古典的ホジキンリンパ腫の臨床症状および診断clinical presentation and diagnosis of classic hodgkin lymphoma in adults [show details]
… PET/CT is used for staging cHL, as described separately. A tissue biopsy is required to diagnose cHL and to determine the histologic subtype. The site and type of biopsy is informed… Grading schemes and other features of the cellular infiltrate that may have prognostic significance for cHL are described separately. Hodgkin/Reed-Sternberg (HRS) cell… Mixed cellularity cHL (MCCHL) is a heterogeneous subtype of classic HL with a diffuse or vaguely nodular growth…
5. ホジキンリンパ腫の発症機序pathogenesis of hodgkin lymphoma [show details]
… from approximately 75 percent in mixed cellularity cHL and lymphocyte-depleted cHL to 10 to 25 percent in nodular sclerosing cHL .… The malignant cells of cHL are called Hodgkin/Reed-Sternberg (HRS) cells and they account for only a small fraction of the cellular infiltrate (estimated to be 0.1…