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1. COX-2選択的阻害薬の概要overview of cox 2 selective nsaids [show details]
… comparably therapeutic doses. Detailed information regarding these trials is presented elsewhere. A possible concern regarding selective COX-2 inhibition is the potential to delay healing of gastric erosions …
2. 美容適応としてのボツリヌス毒素投与の概要overview of botulinum toxin for cosmetic indications [show details]
… botulinum toxin is dose-dependent. In a randomized trial that compared two different doses of rimabotulinumtoxinB, the duration of efficacy was longer with the higher dose (10 to 12 weeks… Impairment of muscle action with botulinum toxin before resurfacing may improve healing and collagen remodeling after laser treatment,…
3. プロトンポンプ阻害薬：胃酸分泌が関与する疾患への使用と副作用の概要proton pump inhibitors overview of use and adverse effects in the treatment of acid related disorders [show details]
…examining the relative effectiveness of different PPI doses and dosing regimens found no consistent difference in symptom resolution and esophagitis healing rates . In patients unable to swallow pills or capsules …
4. 確実な骨折マネージメントの一般原則general principles of definitive fracture management [show details]
… vitamin D is prescribed, a daily dose of 1000 international units during fracture healing seems reasonable. Cigarette smoking and excessive alcohol use impairs fracture healing. Patients should be encouraged …
5. 難治性消化性潰瘍に対するアプローチapproach to refractory peptic ulcer disease [show details]
… respond to standard doses of PPI (eg, omeprazole 40 mg daily), twice-daily dosing is usually effective in inducing healing. We perform a repeat endoscopy to document ulcer healing following 12 additional …

Japanese Journal

AKT阻害剤とCdk4阻害剤によるヒトがん細胞の放射線耐性の抑制

志村勉,角田智,落合靖史,桑原義和,高井良尋,福本学
日本放射線影響学会大会講演要旨集 2010(0), 142-142, 2010
… 通常の放射線療法は、がんの治癒線量と正常組織への副作用を考慮して行うため、Ｘ線、１日2 Gyの繰り返しで、合計60 Gy程度のＸ線分割照射からなっている。 …
NAID 130007001398

腫瘍不均一性が与える低および高LET放射線生物効果への影響（第３報）

小池幸子,安藤興一,鵜澤玲子,古澤佳也,平山亮一,松本孔貴,吉田光明,岡安隆一
日本放射線影響学会大会講演要旨集 2010(0), 292-292, 2010
… ガンマ線による＜100:0＞腫瘍の50%腫瘍治癒線量（TCD50）は81Gyだが＜0:100＞腫瘍では99Gyであり、また炭素線ではそれぞれ33Gyと43Gyであった。 …
NAID 130007000732