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1. 選択的エストロゲン受容体モジュレーター・受容体ダウンレギュレーターの作用機序mechanisms of action of selective estrogen receptor modulators and down regulators [show details]
… The ER shares many structural features with other members of the nuclear receptor superfamily with six components or "domains,"… maintaining the receptor in a protein/DNA complex that does not promote transcription . ER coactivators are exquisitely sensitive to the conformational…
2. 甲状腺ホルモンの作用thyroid hormone action [show details]
… TRs. Examples of coactivators are SRC (steroid receptor coactivator) and CBP (CREB [cAMP response element-binding protein]-binding protein). Examples of corepressors are NCoR (nuclear corepressor) and …
3. 去勢抵抗性前立腺癌：アンドロゲンのシグナル経路を標的にする療法castration resistant prostate cancer treatments targeting the androgen pathway [show details]
…amplification of the androgen receptor gene , increased sensitivity of the androgen receptor via overexpression of nuclear coactivators , and splice variant mutations of the receptor , have been proposed and may …
4. エストロゲン作用の分子生物学および生理学molecular biology and physiology of estrogen action [show details]
… coupled between membrane-bound growth factor receptor pathways and nuclear receptors.… the conformation of the ligand-binding domain of the receptor is altered, allowing interaction with coactivator molecules if the ligand is an agonist,…
5. 喘息における吸入ステロイドの分子学的影響molecular effects of inhaled glucocorticoid therapy in asthma [show details]
…inflammatory enzymes, and receptors. Such genes are switched on when a coactivator molecule (eg, CREB-binding protein) binds to a proinflammatory transcription factor (eg, nuclear factor-kappa B [NF-kB], …

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リンク元	「核内受容体コアクチベーター2」「nuclear receptor coactivator 2」「核内レセプター転写共役因子2」
関連記事	「核内レセプターコアクチベーター」「内」「コア」「核内」