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1. 肺末梢病変の画像誘導下肺生検のための気管支鏡検査image guided bronchoscopy for biopsy of peripheral pulmonary lesions [show details]
… Peripheral pulmonary nodules or lesions (PPLs; also known as peripheral lung lesions [PLLs]) are difficult to biopsy using a conventional flexible bronchoscope.… target lesion is reached. This allows the bronchoscope to be advanced branch-by-branch through the airway to the target lesion. Biopsy phase – Depending on the procedure chosen to biopsy the lesion,…
2. 小児における急性上気道閉塞の緊急評価emergency evaluation of acute upper airway obstruction in children [show details]
… approach to acute upper airway obstruction in children. The emergent evaluation of children with acute respiratory distress and airway management techniques for the difficult pediatric airway are discussed separately …
3. 成人の気道疾患のマネージメントにおける気管支内光線力学的療法endobronchial photodynamic therapy in the management of airway disease in adults [show details]
… inoperable, peripheral lung cancer. Since a lesion requires direct illumination for photodynamic therapy (PDT) to be effective, airway obstruction solely due to extrinsic compression of the airway is a contraindication …
4. 小児のチアノーゼへの治療アプローチapproach to cyanosis in children [show details]
… causes of peripheral cyanosis in otherwise healthy neonates and young infants. Fever – Fever may be present in children with infectious causes of cyanosis secondary to upper airway obstruction… those infants with lesions dependent upon a patent ductus arteriosus for pulmonary blood flow (eg,…
5. 救急外来における急性の筋力低下を訴える成人の評価evaluation of the adult with acute weakness in the emergency department [show details]
… Hemiparesis suggests a hemispheric lesion; paraparesis suggests a spinal cord lesion. Peripheral nerve disease,… volume before upper airway weakness develops, resulting in an increased respiratory rate to maintain minute ventilation . The decision to secure the airway of patients with respiratory…

Japanese Journal

Mepolizumabが有効であった細気管支病変を伴う気管支喘息の1例

大山バク,粒来崇博,駒瀬裕子,西田晧平,鶴岡一,薄場彩乃,村岡弘海,檜田直也,峯下昌道
アレルギー 68(2), 101-106, 2019
… の好酸球増多を認めたが，気管支肺胞洗浄および気管支肺胞組織では好酸球浸潤は明らかではなかった．気管支喘息に伴う細気管支病変と診断，Mepolizumab 100mg/月で治療を開始したところ，症状，呼吸機能，末梢血好酸球増多，小葉中心性陰影の改善を認めた．ICSは吸入薬であるため末梢気道に届きにくく，抗炎症療法が不十分となりうる．Mepolizumabは気管支喘息の末梢気道病変について有効であると考えられた．</p> …
NAID 130007612791