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1. 新生児における腎石灰化症nephrocalcinosis in neonates [show details]
…activity of furosemide. Concurrent therapy with acetazolamide, which inhibits carbonic anhydrase, diminishes proximal tubular transport of calcium, phosphate, and bicarbonate. The net effect appears to be …
2. 骨軟化症の疫学および病因epidemiology and etiology of osteomalacia [show details]
… Renal phosphate wasting can occur as part of an overall defect in proximal tubular transport in the Fanconi syndrome or in primary renal phosphate wasting syndromes.… type 2 renal tubular acidosis, and excessive exposure to inhibitors of bone mineralization (eg,…
3. 小児の高カリウム血症の原因、臨床症状、診断、評価causes clinical manifestations diagnosis and evaluation of hyperkalemia in children [show details]
… only the renal tubular function is affected and its clinical impact may wane as the child grows with further maturation of tubular sodium transport.… spironolactone or eplerenone) or one of the angiotensin converting enzyme inhibitors or angiotensin receptor blockers may develop hyperkalemia…
4. 成人における低カリウム血症の原因causes of hypokalemia in adults [show details]
… Mutations in a variety of tubular transport proteins can mimic the effects of chronic therapy… Any diuretic that acts proximal to the potassium secretory site – carbonic anhydrase inhibitors (eg,…
5. 小児における低カリウム血症hypokalemia in children [show details]
…potassium secretion. Genetic tubular disorders – Bartter and Gitelman syndromes are autosomal recessive diseases that are caused by mutations in genes encoding tubular transport proteins involved in sodium …