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1. 筋萎縮性側索硬化症およびその他の運動ニューロン疾患の臨床的特徴clinical features of amyotrophic lateral sclerosis and other forms of motor neuron disease [show details]
… upper and lower motor neuron signs and symptoms. The upper motor neuron findings of weakness with slowness, hyperreflexia, and spasticity result from degeneration of frontal lobe motor neurons located in the …
2. 筋萎縮性側索硬化症およびその他の運動ニューロン疾患の診断diagnosis of amyotrophic lateral sclerosis and other forms of motor neuron disease [show details]
… prominent finding that reflects reinnervation. Muscle cell type (fast, slow, or intermediate twitch) is determined by the innervating motor neuron and leads to characteristic staining intensities. Normally,…
3. 筋萎縮性側索硬化症の疫学および病因epidemiology and pathogenesis of amyotrophic lateral sclerosis [show details]
… ALS-FTD, and non-tau FTD. Immunoreactive inclusions to FUS in spinal motor neurons have been detected in both sporadic and familial ALS, with the exception of those associated with SOD1 variants . Earlier …
4. 家族性筋萎縮性側索硬化症familial amyotrophic lateral sclerosis [show details]
… Amyotrophic lateral sclerosis (ALS) is one specific type of the more general group of motor neuron diseases. These disorders variably affect motor neurons located in the anterior (ventral) horn regions …
5. 筋萎縮性側索硬化症の症状に基づくマネージメントsymptom based management of amyotrophic lateral sclerosis [show details]
… although post hoc analysis suggested a possible effect in fast-progressing patients .… Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that causes muscle weakness,…