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1. 小児における皮膚蒼白の評価evaluation of pallor in children [show details]
… red cells are markedly microcytic and show substantial variation in size and shape. Elongated red cells (pencil forms) are common.… rheumatologic disorders. In the examination of the severely anemic patient, pallor of the skin and mucous membranes usually is readily apparent. When anemia is less severe or when the skin color is dark …
2. 原発性免疫不全の胃腸症状gastrointestinal manifestations in primary immunodeficiency [show details]
… epithelium by forming complexes with attachment sites for epithelial cells on the surface of micro-organisms . Trapping antigens from micro-organisms and dietary proteins in the mucus,… of chronic granulomatous disease, specifically if accompanied by anemia, which is most commonly microcytic and hypochromic. Anemia may be present due to chronic infection, blood loss, or autoimmune hemolytic …
3. 皮膚の良性病変の概要overview of benign lesions of the skin [show details]
… and fissures and ridges forming a cerebriform pattern Biopsy may be necessary if… soft papules or nodules A digital myxoid cyst or myxoid pseudocyst (also called mucous or mucoid cyst) typically presents as a translucent…
4. von Willebrand病の臨床症状および診断clinical presentation and diagnosis of von willebrand disease [show details]
… plug forms on a membrane with a central aperture that is coated with collagen and another platelet agonist, either ADP or epinephrine. The time to closure of the aperture as the platelet plug forms is measured… 105 infants and toddlers diagnosed with VWD at age <2 years, 70 percent had a bleeding event . Oral mucous membrane bleeding was the most common site, affecting one-third. Bleeding with circumcision affected … Microcytic anemia – Individuals with heavy menstrual bleeding or gastrointestinal bleeding may develop iron deficiency or iron deficiency anemia, with microcytosis.…
5. 先進国に居住する成人の急性下痢へのアプローチapproach to the adult with acute diarrhea in resource rich settings [show details]
… evaluating volume status and identifying complications. Volume depletion can be suggested by dry mucous membranes, diminished skin turgor, postural or frank reductions in blood pressure, and altered sensorium …