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1. ヘモグロビンと酸素の親和性を変化させるヘモグロビン変種hemoglobin variants that alter hemoglobin oxygen affinity [show details]
… more than 4 g/dL higher. Specific high oxygen affinity variants are discussed below. Low oxygen affinity – A high p50 is consistent with a low oxygen affinity variant; these individuals typically have cyanosis …
2. 非膵島細胞腫瘍性低血糖nonislet cell tumor hypoglycemia [show details]
… Hypoglycemia can be caused by several tumors, including islet and nonislet tumors. Nonislet cell tumor hypoglycemia (NICTH) is a rare but serious complication of malignancy . The most common cause of …
3. 組織に依存しないがん治療：固形がんにおけるDNAミスマッチ修復の欠損、腫瘍変異量および免疫チェックポイント遮断への応答tissue agnostic cancer therapy dna mismatch repair deficiency tumor mutational burden and response to immune checkpoint blockade in solid tumors [show details]
… dMMR cancer subsets without specific regard to tumor type. Subsequently, in June 2020, pembrolizumab approval was extended to tumors with high levels of tumor mutational burden (TMB). This topic provides …
4. 成人のクローン病の治療：腫瘍壊死因子a阻害薬の用法・用量とモニタリングtreatment of crohn disease in adults dosing and monitoring of tumor necrosis factor alpha inhibitors [show details]
… comprised of 75 percent human and 25 percent murine sequences, which has a high specificity for and affinity to tumor necrosis factor (TNF)-alpha. Infliximab neutralizes the biologic activity of TNF-alpha by inhibiting …
5. 転移性の高分化型膵管系神経内分泌（カルチノイド）腫瘍：腫瘍増殖およびホルモン過剰分泌による症状を管理するための全身治療の選択肢metastatic well differentiated pancreatic neuroendocrine tumors systemic therapy options to control tumor growth and symptoms of hormone hypersecretion [show details]
… subset of well-differentiated tumors with a proliferative rate that places them in the high-grade category (G3 NETs). These tumors have a clinical behavior that… with greater binding affinity for SSTR-1, SSTR-3, and SSTR-5,and lower affinity for SSTR-2,…