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1. 心筋における興奮収縮連関excitation contraction coupling in myocardium [show details]
…much larger quantity of calcium from the primary intracellular store of calcium, the sarcoplasmic reticulum (SR), through SR calcium release channels. The sarcolemmal calcium channel and the SR calcium release …
2. ミトコンドリアの構造、機能、および遺伝学mitochondrial structure function and genetics [show details]
…mitochondrial membrane interacts with the endoplasmic reticulum through specialized lipid raft domains termed MAMs (mitochondria-associated endoplasmic reticulum membranes) . MAMs have roles in lipid biosynthesis …
3. ビタミンKおよびその合成ならびにガンマカルボキシグルタミン酸の機能vitamin k and the synthesis and function of gamma carboxyglutamic acid [show details]
…protein is routed through the rough endoplasmic reticulum during biosynthesis; The cell has the carboxylase enzyme associated with the rough endoplasmic reticulum; There are Glu sites within 40 residues of …
4. ダリエ病darier disease [show details]
…both sexes and all ethnic groups. Mutations in the ATP2A2 gene that encodes a sarco/endoplasmic reticulum Ca²⁺-adenosine triphosphate (ATP)ase pump (SERCA2) lead to both acantholysis and apoptosis …
5. ペリツェウス・メルツバッハー病pelizaeus merzbacher disease [show details]
…rough endoplasmic reticulum and modified in the Golgi complex prior to transport to the myelin membrane. Thus, the accumulation of misfolded PLP and DM20 in the endoplasmic reticulum leads to the expression …