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1. 抗好中球細胞質抗体の臨床的な意味clinical spectrum of antineutrophil cytoplasmic autoantibodies [show details]
… The relationship between antineutrophil cytoplasmic autoantibodies (ANCA) and granulomatosis polyangiitis (GPA), microscopic polyangiitis (MPA), and "renal-limited" vasculitis (pauci-immune glomerulonephritis …
2. 抗好中球細胞質自己抗体関連血管炎の病因pathogenesis of antineutrophil cytoplasmic autoantibody associated vasculitis [show details]
… The antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides include granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis …
3. 遺伝学の基礎概念：染色体と細胞分化basic genetics concepts chromosomes and cell division [show details]
… and the mitotic spindle forms from an array of microtubules. The "minus" ends of the microtubules collect at two separate poles,… dividing cells must pass in order to distribute genetic material to daughter cells, along with cytoplasmic proteins and organelles, with high fidelity. The DNA replication phase is referred to as "S" (for …
4. 前頭側頭型認知症：疫学、病理学、および病因frontotemporal dementia epidemiology pathology and pathogenesis [show details]
…mutation . Tau protein is encoded by the MAPT gene on chromosome 17. Tau stabilizes microtubules, promotes microtubule assembly, and regulates axonal transport . Tau protein is alternatively spliced into … This pathologic entity can be subdivided according to the nature of the characteristic cytoplasmic or nuclear protein inclusions that are observed histopathologically…
5. パーキンソン病の病因および発症機序etiology and pathogenesis of parkinson disease [show details]
…"dardara," meaning tremor) that probably functions as a cytoplasmic kinase involved in phosphorylation of proteins, such as alpha-synuclein and microtubule-associated protein tau . Dardarin is a large molecule …

Japanese Journal

ショウジョウバエの巨大ミトコンドリアが促進する精子形態形成

野口立彦
顕微鏡 = Microscopy 47(4), 191-195, 2012-12-30
… メカニズムについて解析した．この精子伸長は特殊であり，精子運動に必須の鞭毛軸糸ではなく，巨大ミトコンドリアと細胞質微小管が内骨格として細胞伸長を促進することが判明した．巨大ミトコンドリア自身が微小管重合中心として働き，ミトコンドリア周囲の細胞質微小管がモータータンパク質と滑り運動を起し，伸長力を発生する．つまりショウジョウバエの長大な精子形成において，ミト …
NAID 10031144737