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1. 去勢抵抗性前立腺癌への二次内分泌療法の種類alternative endocrine therapies for castration resistant prostate cancer [show details]
…sequential fashion after bicalutamide. Nilutamide is often the second antiandrogen used, although it can cause problems with light-dark adaptation, and there is a risk of pulmonary toxicity. Flutamide is seldom …
2. 網膜色素変性症：臨床症状および診断retinitis pigmentosa clinical presentation and diagnosis [show details]
… sensitivity to light increases again until a second plateau is reached. Abnormalities of dark adaptometry in RP include loss of rod sensitivity,… the earliest symptoms . Patients may notice that they become disoriented in dim light, or that adaptation to dim light is slow, as in movie theaters. However, night blindness may go unrecognized until …
3. 短腸症候群の病態生理pathophysiology of short bowel syndrome [show details]
…such as high concentrations of simple carbohydrates. Intestinal adaptation – The ileum has a greater capacity for intestinal adaptation compared with the jejunum . The ileocecal valve acts as a barrier …
4. 頭頸部癌患者における二次発癌second primary malignancies in patients with head and neck cancers [show details]
…observed to expected second cancers . The most frequent second malignancy was lung cancer (20-year cumulative risk 13 percent, SIR 3.3). The highest relative increase in risk was for a second head and neck …
5. セロトニン再取り込み阻害剤（SSRI）およびセロトニン・ノルアドレナリン再取り込み阻害薬（SNRI）への出生前曝露：新生児の転帰antenatal exposure to selective serotonin reuptake inhibitors ssris and serotonin norepinephrine reuptake inhibitors snris neonatal outcomes [show details]
…neonatal adaptation . Genetic factors – Poor neonatal adaptation may be associated with genetic polymorphisms . Infants who are exposed in utero to SSRIs and then develop poor neonatal adaptation may perhaps… SSRIs and SNRIs are first- and second-line medications for unipolar depressive disorders and anxiety disorders,…