UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 表在性シデローシスsuperficial siderosis [show details]
…breaks down into globin and neurotoxic heme . In response to the presence of neurotoxic heme, Bergmann glia and microglia release heme oxygenase-1 and apoferritin. Heme oxygenase-1 breaks heme into free iron …
2. 健常者および疾患を有する患者における消化管ホルモンの概要overview of gastrointestinal peptides in health and disease [show details]
…neurofilaments and contain large numbers of secretory vesicles and abundant mitochondria . They are escorted by glia, suggesting they directly communicate with other nearby cells including neurons. Regulation of gastrointestinal…
3. メタンフェタミン使用障害：疫学、臨床症状、経過、評価、および診断methamphetamine use disorder epidemiology clinical manifestations course assessment and diagnosis [show details]
…space) Excitotoxic mechanisms (eg, excessive glutamate) Neuroinflammation (eg, inflammation of the glia) Ubiquitin proteasome system, dysfunctional recycling of proteins; Mitochondrial dysfunction (eg, …
4. 小児における中枢神経系腫瘍の疫学epidemiology of central nervous system tumors in children [show details]
…tumors carry an extremely poor prognosis. Ependymomas – Ependymal tumors are derived from primitive glia. Ependymomas account for 10 percent of intracranial tumors and 40 to 60 percent of spinal cord tumors…
5. 多系統萎縮症：臨床的特徴および診断multiple system atrophy clinical features and diagnosis [show details]
…One postulated mechanism involves prion-like spreading of aberrant alpha-synuclein from neurons to glia through functionally connected networks, thereby leading to glial and myelin dysfunction and an inflammatory …