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1. 意義未確定の単クローン性免疫グロブリン血症（MGUS）の診断diagnosis of monoclonal gammopathy of undetermined significance [show details]
… LC-MGUS may progress to light chain smoldering multiple myeloma (idiopathic Bence Jones proteinuria) and to light chain multiple myeloma,…g/dL, a bone marrow with <10 percent monoclonal plasma cells, and absence of end-organ damage (lytic bone lesions, anemia, hypercalcemia, renal insufficiency, hyperviscosity) related to the proliferative process …
2. 糖尿病性神経障害性関節症diabetic neuropathic arthropathy [show details]
… leading to osteolysis of phalanges and to a variety of further changes, including partial or complete disappearance of the metatarsal heads or “pencil-pointing” of phalangeal and metatarsal… condition will be described here. These include septic arthritis, gout, cellulitis, osteoarthritis, idiopathic inflammatory diseases, and osteomyelitis. Another disorder, complex regional pain syndrome (formerly …
3. 小児や青年に生じる手首の慢性疼痛の原因causes of chronic wrist pain in children and adolescents [show details]
… Repetitive loading of the extended wrist can lead to stress and eventual osteolysis of the distal radial growth plate.… The wrist and hand are frequently involved in juvenile idiopathic arthritis (JIA).…
4. 多発性骨髄腫：病理生物学的特徴multiple myeloma pathobiology [show details]
…characterized by end-organ damage, which includes hypercalcemia, renal dysfunction, anemia, or lytic bone lesions. In some patients, an intermediate asymptomatic but more advanced premalignant stage referred …
5. 骨サルコイドーシスsarcoidosis of bone [show details]
…frequently affected appendicular skeletal sites are the proximal and middle phalanges of the hands. With phalangeal involvement, patients can experience local pain and tenderness in the affected region, which can … they are also called cystic bone lesions, but this is a misnomer as bony lesions are a result of osteolysis. These multiple small lytic or cystic lesions sometimes result in a "lacy pattern," which is a …