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1. 利尿剤の作用機序mechanism of action of diuretics [show details]
… that loop diuretics bind a chloride site on the carrier ; however, there may be a more complicated mechanism by which furosemide enters the ion-binding pocket and complexes… Henle (20 percent). As a result, it might be expected that a proximally acting diuretic, such as the carbonic anhydrase inhibitor acetazolamide, could induce relatively large losses of sodium and water. However … the reabsorptive capacity of the distal and collecting tubules is relatively limited and,…
2. 慢性腎疾患における鉄欠乏の診断diagnosis of iron deficiency in chronic kidney disease [show details]
… Instead, iron stores are more commonly estimated by: Measurement of serum iron, total iron-binding capacity (TIBC), and ferritin and calculation of the percent transferrin saturation (TSAT) or by Determination …
3. 早産児（妊娠35週未満）の非抱合型高ビリルビン血症unconjugated hyperbilirubinemia in the preterm infant less than 35 weeks gestation [show details]
… reflect the concentration of free (unbound) bilirubin (UB) due to reduced and varied bilirubin binding capacity (BBC) for infants . In this setting, UB testing (if available) or measuring the bilirubin/albumin …
4. 成人における意思決定能力の評価assessment of decision making capacity in adults [show details]
… constitutes an assessment of capacity. The terms capacity and competence are sometimes used interchangeably, but historically they have held separate although overlapping meanings. Capacity is most often used …
5. 尿細管性アシドーシスにおける腎結石症nephrolithiasis in renal tubular acidosis [show details]
… Carbonic anhydrase is important for both proximal and distal acidification. Carbonic anhydrase inhibitors,… defect is a reduction in bicarbonate reabsorptive capacity in the proximal tubule .…