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1. 甲状腺ホルモンの合成および生理thyroid hormone synthesis and physiology [show details]
…pituitary than it does in many other tissues . T4 and T3 inhibit the synthesis and release of both TSH and TRH . The inhibition of TSH synthesis is achieved primarily by inhibition of transcription of the TSH …
2. ビタミンKおよびその合成ならびにガンマカルボキシグルタミン酸の機能vitamin k and the synthesis and function of gamma carboxyglutamic acid [show details]
…the sufficiency of the gamma-carboxylation recognition site within the propeptide in directing synthesis of gamma-carboxyglutamic acid on the adjacent Gla domain of the precursor protein. Additional advances…
3. 遺伝学およびゲノミクスのためのツール：モデルシステムtools for genetics and genomics model systems [show details]
…conformation during synthesis; misfolded proteins lose function. So-called "chaperone" proteins interact with nascent peptides to assist in their correct folding during protein synthesis.… systems to explore the relationship between genetic constitution and function.…
4. 鉄芽球性貧血の原因および病態生理causes and pathophysiology of the sideroblastic anemias [show details]
…impairment of heme synthesis through the effect of alcohol on vitamin B6 metabolism as well as on subsequent steps of heme synthesis . Toxic effects on mitochondrial protein synthesis may also be involved …
5. 副腎ステロイド生合成adrenal steroid biosynthesis [show details]
…enzymes involved in adrenal steroid hormone synthesis. It is also critical for understanding the mechanisms of action of drugs directed at reducing cortisol synthesis in patients with Cushing syndrome . The …