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1. 成人の潰瘍性大腸炎治療に用いる生物学的製剤や低分子医薬品の用量およびモニタリングの概要overview of dosing and monitoring of biologic agents and small molecules for treating ulcerative colitis in adults [show details]
… tofacitinib can be increased to 10 mg twice daily for a maximum of 16 weeks before decreasing the dose to 5 mg twice daily.… The suggested target drug trough concentrations are primarily based on cross-sectional…
2. 肝疾患を有する患者における化学療法による肝毒性および用量調整：分子標的薬chemotherapy hepatotoxicity and dose modification in patients with liver disease molecularly targeted agents [show details]
… and dose reduction may be needed for patients with moderate to severe liver dysfunction. In a phase I study of 98 patients with hepatic dysfunction treated with pazopanib, the maximum tolerated dose in… and require dose reduction in the setting of baseline hepatic impairment. The interrelationship between the liver and molecularly targeted agents used for cancer…
3. 直接経口抗凝固薬（DOAC）と非経口直接作用型抗凝固薬：用量および副作用direct oral anticoagulants doacs and parenteral direct acting anticoagulants dosing and adverse effects [show details]
… Dabigatran is generally given at a fixed dose without monitoring It is important to use the appropriate dose (ie, do not under-dose). Maximum anticoagulant effects are achieved… and after any dose changes. The dose is adjusted to achieve a target aPTT of 1.5…
4. 成人の炎症性腸疾患患者へのブデソニド療法の概要overview of budesonide therapy for adults with inflammatory bowel disease [show details]
…budesonide is absorbed in the proximal small bowel and cannot be delivered to the site of inflammation. Oral budesonide formulations are engineered to be resistant to gastric acid and allow for targeted,… systemic bioavailability of the drug is decreased. This topic will review the pharmacology, indications, dosing, and safety of budesonide in the management of chronic, inflammatory bowel disease (IBD). The efficacy … budesonide and its use only as induction therapy (maximum treatment duration of three months).…
5. イソニアジド：概要isoniazid an overview [show details]
… The usual adult dose of INH is 5 mg/kg orally once daily; the usual pediatric dose is 10 to 15 mg/kg orally per day, up to a maximum of 300 mg daily. Higher single doses (ie,… is well absorbed after oral administration (approximately 90 percent). Peak serum concentrations occurring 0.5 to 2 hours after an oral dose range from 3 to 6 mcg/mL after a 300 mg dose and from…

「吸収線量」

英: absorbed dose
関: シーベルト、グレイ Gy

単位：グレイ Gy、ラド rad

	単位		意味
吸収線量	グレイ	Gy	物質が吸収するエネルギーの量
等価線量	シーベルト	Sv	吸収されたエネルギーが生体に与える影響を、線種により補正
実効線量	シーベルト	Sv	吸収されたエネルギーが生体に与える影響を体部位、臓器により補正。総和で実質吸収した線量が計算される。