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1. 食物中の微量元素の概要overview of dietary trace elements [show details]
…and ultimately death . In children, as little as 8.4 mg/kg may produce symptoms . Chronic fluoride toxicity (fluorosis) is usually caused by high fluoride concentrations in drinking water or the use of …
2. 乳幼児への予防的デンタルケアおよびカウンセリングpreventive dental care and counseling for infants and young children [show details]
… Severe fluorosis is much less common than mild fluorosis, but it can make the teeth more susceptible to wear and breakage . The mechanism by which excessive fluoride consumption causes fluorosis appears… it remains one of the most common chronic diseases in children of all age groups.…
3. 骨軟化症の疫学および病因epidemiology and etiology of osteomalacia [show details]
…phosphate wasting, is the most common cause of osteomalacia. Normal pH at the site of calcification. Chronic acidosis, as occurs in renal tubular acidosis, causes bone disease. Adequate bioactivity of alkaline … as may occur in endemic fluorosis and with ingestion of fluoride toothpastes and certain teas .…
4. 成人における低カルシウム血症の原因etiology of hypocalcemia in adults [show details]
…physiologically important ionized (or free) calcium concentration. As an example, in volume overload, chronic illness, and malnutrition or nephrotic syndrome (where serum protein can be reduced), total plasma …
5. 血液透析に使用される水の混入物質contaminants in water used for hemodialysis [show details]
… spasms; Personality changes; Seizures; Dementia; Chronic exposure to aluminum is also associated with severe… although fluoride has been associated with skeletal fluorosis in certain populations and possible kidney damage in children .…