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1. 胸腺腫および胸腺癌の臨床症状およびマネージメントclinical presentation and management of thymoma and thymic carcinoma [show details]
… is uncommon . Nonetheless, surgical resection of the thymoma is usually undertaken if pure red cell aplasia is found. The management of pure red cell aplasia is discussed separately. Immunodeficiency …
2. 縦隔腫瘤が発生した成人患者へのアプローチapproach to the adult patient with a mediastinal mass [show details]
… years (eg, thymoma in some patients) or rapid expansion (eg, lymphoma). Mediastinal masses can also be associated with abnormalities in other parts of the body (eg, testicular masses with germ cell tumors); …
3. 縦隔腫瘍の病理pathology of mediastinal tumors [show details]
… of large, polygonal tumor cells that may show increased cytologic atypia and only a few or no scattered lymphocytes. These thymomas have a prognosis that is worse than that of other thymomas but better …
4. リンパ球増加症またはリンパ球減少症を有する成人に対するアプローチapproach to the adult with lymphocytosis or lymphocytopenia [show details]
… years . Thymoma is a thymic malignancy that typically affects middle-aged adults and may be associated with paraneoplastic autoimmune syndromes (eg, myasthenia gravis, pure red cell aplasia). Thymoma is occasionally …
5. 成人の後天性赤芽球ろうacquired pure red cell aplasia in adults [show details]
… leukemia, but others had idiopathic PRCA, thymoma, or an autoimmune disorder. In the individuals with STAT3 mutation, the mutation was isolated to CD8-positive T cells. Acquired PRCA in adults can be divided …

「胸腺腫」

　　[★]

英: thymoma, thymomas
関: 胸腺、縦隔腫瘍

概念

上縦隔の前部、前縦隔の前部に発生
胸腺固有の上皮細胞が腫瘍化したもの。precursor T cell(thymocytes)も存在することがあるが、悪性ではない。

分類

begign or encapsulated thymoma

malignant thymoma
type I: cytologically benign but biologically aggressive and capable of local invasion and, rarely, distant spread
type II: also called thymic carcinoma: cytologically malignant with all of the features of cancer and comparable behavior

HIM. e89

型	組織型	割合,%	予後(10-year disease-free survival), %
A	medullary thymoma	8	100
AB	mixed thymoma	17	100
B1	predominantly cortical thymoma	27	83
B2	cortical thymoma	8	83
B3	well-differentiated thymic carcinoma	12	36
C	thymic carcinoma	28	28