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1. 食物中の微量ミネラルの概要overview of dietary trace minerals [show details]
… was ultimately found to be chromium (Cr). Chromium is a transition element and exists in multiple ionic states. Dietary chromium is in the trivalent state.… peripheral tissues, but it may be bound to transferrin . Approximately one-quarter of total body manganese is found in the bones . Significant amounts also are found in tissues rich in mitochondria…
2. 拡張型心筋症の原因causes of dilated cardiomyopathy [show details]
… – 4 percent; HIV infection – 4 percent; Connective tissue disease – 3 percent; Substance abuse – 3 percent;… concentration of mercury (22,000 times normal), antimony (12,000-fold higher), gold (increased 11-fold), chromium (13-fold higher), and cobalt (4 times higher). By comparison, patients with valvular or ischemic … shifting endogenous beta-1 adrenoceptors into the agonist-coupled high-affinity state,…
3. アレルギー性接触皮膚炎の基本的機序および病態生理basic mechanisms and pathophysiology of allergic contact dermatitis [show details]
… one of the most common ACD-associated haptens; and chromium [Cr]³⁺) are also well-known electrophiles.… ability of haptens include lipophilicity, tridimensional chemical structure, and protein-binding affinity. The most reactive nucleophilic side chains of proteins are found on lysine, cysteine, and histidine … They reside in the skin and other tissues and are emerging as another cell type that may play…
4. 喫煙と肺癌の発症につながるその他の危険因子cigarette smoking and other possible risk factors for lung cancer [show details]
…Other exposures that have been associated with lung cancer include arsenic, bis(chloromethyl) ether, chromium, formaldehyde, ionizing radiation, nickel, polycyclic aromatic hydrocarbons, hard metal dust, and … Improved RT techniques limit the dose of radiation to nonmalignant tissue,…
5. 2型糖尿病の危険因子risk factors for type 2 diabetes mellitus [show details]
… Chromium deficiency is generally limited to hospitalized patients with increased catabolism and metabolic demands in the setting of malnutrition. Other patients at risk for chromium deficiency… The distribution of excess adipose tissue is another important determinant of the risk of insulin resistance and type 2 diabetes.…